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This study found that targeting CISD1 with the compound NL-1 reduced mitochondrial dysfunction and reactive oxygen species accumulation, protecting against cisplatin-induced hearing loss in cell models and mice, without affecting cisplatin's cancer-fighting effectiveness.

This study found that fatty acid desaturation regulated by SCD1 is crucial for hair growth by maintaining hair follicle stem cell niches, with its absence causing abnormal hair growth in mice.

This study found that Low Power Laser therapy may be an effective complementary treatment for scalp alopecia and crural ulcers, showing quicker and potentially better results than conventional treatments.

This study found that cutaneous signs such as chilblains and urticaria were notably common in British patients with systemic lupus erythematosus, while subacute cutaneous lesions were less frequent.

In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.

The number of new cases of cutaneous B-cell lymphoma has leveled off since the early 2000s, and survival rates have improved since 1973.

This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.

This correspondence describes two patients with both epidermolysis bullosa simplex, Dowling-Meara type, and loose anagen hair syndrome, an association not previously reported in the literature.

This study found that the ocular surface epithelium in mice contains distinct stem cell populations with unique cell division dynamics that change behaviorally in response to different levels of injury.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

This study found that LGR5 is uniquely expressed in human corneal endothelial cells and maintains endothelial cell phenotypes while inhibiting mesenchymal transformation through the Wnt pathway.

This research identified a genetic mutation in Brachypodium distachyon that initially allows root hair initiation but fails to elongate them, while also affecting root growth and nitrate sensitivity; the mutation is linked to a previously uncharacterized cyclin-dependent kinase-like gene.

This study identified specific germline and somatic mutations in the Phospholipase C Delta 1 gene as high-risk factors for developing hereditary trichilemmal cysts, involving a monoallelic two-hit mechanism.

PCFCL may have unrecognized subtypes and needs more research.

This research reported that liposomal systems made from pig-derived skin lipids enhanced finasteride delivery to hair follicles for treating androgenetic alopecia, showing improved drug deposition, hair length, and growth compared to conventional finasteride forms in vitro.

This study confirmed linkage of Clouston syndrome in a large Indian family to the 13q11-12.1 region, suggesting it shares a genetic basis with French Canadian cases.

This study found that sodium selenite induced both subacute and chronic selenosis in cow calves, significantly affecting specific haematological parameters, with more pronounced alterations observed in chronic toxicity.

This case study of a neonate with ichthyosis and ILVASC demonstrates how an interdisciplinary approach facilitated a timely genetic diagnosis and management of complications.

This review discusses the epidemiology and cutaneous manifestations of lupus erythematosus, highlighting comparable incidence rates between cutaneous and systemic forms, but reports no new findings.

This paper suggests intralesional cidofovir as a potentially effective treatment for SCC with no systemic toxicity observed, but surgical excision remains the standard for its curative outcomes and thorough evaluation.

In this study, a machine learning framework incorporating the CatBoost algorithm accurately predicted Systemic Lupus Erythematosus in Omani patients, suggesting potential for early clinical intervention.

Suplatast tosilate successfully treated a woman's systemic sclerosis symptoms.

This study reported that the absence of Lsh in skin led to significant epidermal hyperplasia and altered gene expression, suggesting its crucial role in regulating epidermal proliferation, differentiation, and wound healing.

This research found that LSE transplantation positively affects wound healing by promoting granulation tissue growth and minimizing cosmetic defects in ischemic non-healing wounds during preclinical studies. Additionally, the proposed smoothing coefficient helps assess the degree of wound bed filling with developing tissue.

This study found that combining optical clearing methods with light-sheet fluorescence microscopy allows detailed 3D visualization of normal and pathological human skin biopsies, revealing differences in epidermal thickness and volume.

This report describes two scalp lichen simplex chronicus cases with hair loss and intense itching, noting unique dermoscopic and histopathological features.

This review found that the DLQI is widely used as a benchmark in the development and validation of dermatology quality-of-life measures.

This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.

This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.

This study found that a CLSM-based approach could semi-quantitatively assess the transdermal penetration behavior of fluorescent dyes with different lipophilicities, offering a tool for early-stage screening of compound penetration.