research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats
FGF5 gene mutations cause long hair in domestic cats.
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research Trichoscopy in Genetic Hair Shaft Abnormalities
Trichoscopy is a quick and easy way to diagnose most genetic hair problems without invasive methods.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research Multiple Cyclic Nucleotide-Gated Channels Coordinate Calcium Oscillations and Polar Growth of Root Hairs
Cyclic nucleotide-gated channels are crucial for proper root hair growth and calcium balance in plants.
research Sostdc1 Defines the Size and Number of Skin Appendage Placodes
Sostdc1 controls the size and number of hair and mammary gland structures.
research Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation
A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
research Development and Assessment of an Artificial Intelligence-Based Tool for Skin Condition Diagnosis by Primary Care Physicians and Nurse Practitioners in Teledermatology Practices
The AI tool helped primary care doctors and nurse practitioners diagnose skin conditions more accurately.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
research Epidermal Expression of the Truncated Prelamin A Causing Hutchinson-Gilford Progeria Syndrome: Effects on Keratinocytes, Hair, and Skin
Progerin affects cell shape but not hair or skin in mice.
research Macrophage Ferroportin Is Essential for Stromal Cell Proliferation in Wound Healing
Macrophage iron release is crucial for hair growth and wound healing.
research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
research Female Pattern Alopecia: Current Perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research Disruption of the Temporally Regulated Cloaca Endodermal β-Catenin Signaling Causes Anorectal Malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research Thymol-Loaded PLGA Nanoparticles: An Efficient Approach for Acne Treatment
Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.
research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating
Krt15+ cells in the mouse intestine resist radiation and can start tumors.
research Miz1 Is Required for Hair Follicle Structure and Hair Morphogenesis
Miz1 is essential for proper hair structure and growth.
research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
research Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
research Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hedgehog Signaling Pathway
The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
research B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance
B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
research The Impact of VDR Expression and Regulation In Vivo
VDR regulation varies by tissue and is crucial for its biological functions.