Optimized Methodology to Produce Platelet-Rich Plasma and Perform Platelet Aggregation in Patients With Coronary Artery Disease

September 2024 in “ Cureus ”

Atul Kashyap, Bonu Saikrishna, Bhanu Duggal

platelet-rich plasma light transmission aggregometry platelet aggregation PRP LTA PA

TLDR A new method improves platelet testing for heart disease patients.

The study presents an optimized methodology for preparing platelet-rich plasma (PRP) specifically for use in light transmission aggregometry (LTA) assays. This method utilizes a PRP tube and shows promise for routine measurement of platelet aggregation (PA) in cardiology clinics, particularly for patients with coronary artery disease. The successful optimization suggests that this approach could enhance the accuracy and efficiency of PA assessments in clinical settings.

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