82 citations,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
74 citations,
May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
66 citations,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
66 citations,
March 2009 in “British journal of surgery” Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
39 citations,
April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
32 citations,
November 2016 in “Journal of Dental Research” Pannexin 3 is important for bone formation and the development of bone cells.
23 citations,
July 2021 in “Advances in Therapy” Most people with Alopecia Areata don't get treatment within a year; it's costly and often comes with other health issues.
23 citations,
April 1993 in “Gastroenterology” A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
16 citations,
December 2001 in “Dermatologic Therapy” Alopecia areata has a complex genetic basis that was not fully understood as of 2001.
13 citations,
September 2019 in “Scientific Reports” High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
13 citations,
November 2005 in “Veterinary Dermatology” A dog's skin calcification condition resolved without treatment after a bacterial infection.
12 citations,
January 2021 in “Drugs in R&D” Isotretinoin is effective for treating dissecting cellulitis, but recurrence is common.
11 citations,
January 1993 in “Dermatology” EMS and EF both show similar skin and fascia changes, but EMS has more severe symptoms and nerve inflammation.
8 citations,
January 2008 in “European Journal of Pediatrics” Children with autoimmune gastritis showed improved intestinal health over time and should be checked for other autoimmune conditions.
4 citations,
June 2002 in “Clinical and experimental dermatology” Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.
3 citations,
March 2021 in “JAAD case reports” Switching from adalimumab to ixekizumab improved a patient's psoriasis and reversed hair whitening.
2 citations,
May 2011 in “British Journal of Dermatology” Pellagra, caused by niacin deficiency and presenting with photosensitivity, should be considered in patients with relevant symptoms and risk factors.
1 citations,
August 2023 in “Acta dermato-venereologica” Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.
1 citations,
November 2018 in “Therapeutic Delivery” New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
1 citations,
March 2011 in “Informa Healthcare eBooks” Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.
March 2024 in “Dermatology and therapy” AA patients with comorbid conditions face more severe hair loss and need specific treatments.
September 2023 in “International journal of medicine” AI is revolutionizing healthcare by improving diagnosis, treatment, and monitoring, but still needs close supervision.
November 2022 in “Journal of Education, Health and Sport” The skin's bacteria might influence the development of a hair loss condition called alopecia areata.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” ILC1-like cells can cause alopecia areata by attacking hair follicles.
September 2018 in “Journal of the American Academy of Dermatology” Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.
Some vaccines, like the hepatitis B vaccine, might be linked to the hair loss condition Alopecia Areata, but more research is needed.
January 1989 in “Side effects of drugs annual” Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
119 citations,
July 2016 in “Annals of the New York Academy of Sciences” Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
1 citations,
January 2017 in “Evolutionary studies” Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.