Generalized Calcinosis Cutis Associated with Probable Leptospirosis in a Dog

In 2005, a 6.5-year-old male German Shepherd developed generalized calcinosis cutis, a condition involving skin calcification, after a probable diagnosis of leptospirosis, a bacterial infection. The dog initially showed signs of kidney and liver disease and was treated with antibiotics and supportive care. Following recovery, the dog experienced hair loss and skin lesions that expanded over 20 days. Histological analysis confirmed calcinosis cutis with follicular atrophy. Interestingly, no treatment was administered for the skin condition, yet the lesions resolved on their own within 30 days. This case was significant as it was the third instance of generalized calcinosis cutis in an adult dog after a severe systemic disease, but the first to be linked with a bacterial infection rather than fungal infection like blastomycosis, which was noted in the previous two cases.