January 2021 in “Journal of clinical & experimental dermatology research” This study found that a new propylene glycol-free 5% minoxidil lotion demonstrated good clinical efficacy and very good cosmetic acceptability and tolerability after six months of use in patients with androgenetic alopecia, showing results comparable to traditional formulations containing propylene glycol.
4 citations
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January 2009 in “Eclética Química” This study described a potentiometric titration method for determining minoxidil, which showed recoveries of 97.4 to 98.7% and agreed with chromatographic results within a 90% confidence level.
July 2025 in “Journal of Investigative Dermatology” Low-dose oral minoxidil is safe for the heart in the short term for hair loss patients.
3 citations
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January 1988 in “The Nishinihon Journal of Dermatology” This study found that minoxidil concentrations at 1, 10, and 100 μg/ml inhibited the proliferation of cultured hair follicle cells without causing morphological changes.
April 2024 in “Journal of the American Academy of Dermatology” Low-dose minoxidil helps hair grow longer and thicker in people with short anagen syndrome.
4 citations
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October 2021 in “Journal of The European Academy of Dermatology and Venereology” Low-dose oral minoxidil increases hair density and thickness in people with hair loss.
September 2025 in “Journal of the American Academy of Dermatology” Both 2.5 mg and 5 mg doses of oral minoxidil are effective for hair regrowth in men with hair loss.
1 citations
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September 2021 in “Frontiers in Endocrinology” This case report describes the use of topical minoxidil to successfully promote facial hair growth in a 17-year-old trans male unable to start testosterone therapy, with skin dryness as the only reported side effect.
October 2020 in “El-Minia Medical Bulletin” In this study, 20 patients with androgenetic alopecia experienced clinical improvement characterized by increased hair growth and density after using topical minoxidil for 3 to 12 months, suggesting its effectiveness as a treatment option for both men and women.
19 citations
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May 1979 in “Archives of internal medicine” Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Minoxidil may improve hair transplants and combining treatments could help alopecia areata.
October 2024 in “International Journal of Dermatology” In this meta-analysis, researchers found that oral and topical minoxidil treatments for androgenetic alopecia had similar efficacy in improving hair density and diameter, but oral minoxidil resulted in a higher incidence of hypertrichosis compared to topical use.
May 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a multimodal microemulsion containing minoxidil, diclofenac, and tea tree oil was significantly more effective and stable than minoxidil alone in treating androgenic alopecia over a 32-week period.
January 2025 in “Journal of Drugs in Dermatology” This study found that oral minoxidil is superior to topical minoxidil in terms of ease of use, adherence, and patient satisfaction, without increasing systemic side effects, although it did have a higher incidence of hypertrichosis.
10 citations
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March 2004 in “Journal of the American Academy of Dermatology” The 5% minoxidil solution effectively treated hair loss with good tolerability.
July 2023 in “Archives of Dermatological Research” Minoxidil may help with hair loss caused by cancer treatments.
6 citations
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October 2012 in “PubMed” This study found that while the combination therapy of 3% minoxidil and 0.1% finasteride lotion showed greater improvement in global photographic assessments for androgenetic alopecia, hair counts did not differ significantly from minoxidil alone.
July 1987 in “Reactions (Auckland)” Oral minoxidil may slow male pattern baldness and cause body hair growth, but hair loss can happen after stopping it.
37 citations
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March 1986 in “Acta Dermato Venereologica” In this study, there was no significant difference in hair growth between patients with extensive alopecia areata treated with 1% minoxidil and those receiving a placebo.
July 2026 in “Mendeley Data” Higher doses of oral minoxidil can help hair growth but need careful monitoring for side effects.
January 2014 in “American Journal of Medicine and Medical Sciences” This article discusses the mechanisms of androgenetic alopecia and explores possible explanations for minoxidil's effect on hair growth but reports no new results.
2 citations
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March 1985 in “Journal of The American Academy of Dermatology” Minoxidil solution used on the scalp did not lower blood pressure in patients without hypertension.
123 citations
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February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
October 2013 in “Evidence-Based Practice” This study concluded that minoxidil in various formulations is effective for female pattern hair loss, generally safe, but may cause minor skin irritation, with the foam showing the fewest adverse effects.
July 1989 in “British Journal of Dermatology” Minoxidil helps increase hair growth and density in people with hair loss, with higher concentrations giving better results.
December 2025 in “Actas Dermo-Sifiliográficas” This study suggests that low-dose oral minoxidil is safe and effective in treating COVID-19 associated telogen effluvium, as indicated by a significant decrease in hair-shedding scores over follow-up visits.
October 2022 in “Actas Dermo-Sifiliográficas” 4 citations
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January 1983 in “PubMed” In this case study, a male volunteer with frontal alopecia experienced new hair growth during combined daily treatment with cyproterone acetate and minoxidil, but the new hair was lost after stopping minoxidil.
9 citations
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December 1991 in “Annals of the New York Academy of Sciences” Minoxidil helps hair growth by increasing blood flow and stimulating hair follicles.
January 2010 in “Annals of King Edward Medical University” This study concluded that combination therapy with 5% minoxidil and 0.05% betamethasone dipropionate cream was more effective for hair regrowth in alopecia areata than 5% minoxidil alone.