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Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

First-time mothers had higher stress hormone levels in late pregnancy than mothers who had given birth before.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Higher MIF levels in alopecia areata patients suggest it could be a treatment target and disease predictor.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

Fractional lasers effectively treat alopecia areata, especially when combined with minoxidil or cortisol.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.