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This study found that treating secondary hair follicle stem cells from Arbas cashmere goats with 10 μg/mL quercetin for 48 hours significantly boosted cell proliferation and reduced apoptosis by activating several signaling pathways, suggesting a potential strategy to enhance cashmere production.

This study found that treating secondary hair follicle stem cells from Arbas cashmere goats with quercetin at 10 μg/mL for 48 hours significantly enhanced cell proliferation and reduced apoptosis, suggesting potential strategies to improve cashmere production through various signaling pathways.

This study found that surgical removal of adrenal glands resolved clinical signs of adrenocortical tumors and hyperplasias in ferrets, but cortisol levels were not excessively high.

This study found that quercetin significantly promoted proliferation and inhibited apoptosis of hair follicle stem cells from Arbas cashmere goats, suggesting potential benefits for improving cashmere production.

This study found that the WIF1 gene may play a crucial role in hair follicle growth and development in Angora rabbits by regulating specific genes and proteins.

This study found that caffeic acid amide derivative, compound 4, effectively inhibited steroid 5α-reductase type 1 in vitro, suggesting potential for development as a treatment for androgenic alopecia.

This source provides supplementary materials for the Carnivore Follicular Integrity Framework, a theoretical model proposing that animal-based diets may support hair follicle stability through several biological mechanisms. The materials include definitions, nutrient tables, and mechanistic notes but do not report empirical results.

This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.

This study found that overexpression of the FA2H gene in cashmere goats' hair follicle cells may enhance hair proliferation and regulate genes affecting cashmere fineness.

This study identified eight isoflavone derivatives as potential nonsteroidal inhibitors of rat 5α-reductase using a pharmacophore model in virtual screening.

This study found that FGF5-/- rabbits exhibited a significant long hair phenotype by prolonging the anagen phase, suggesting FGF5 acts as a negative regulator of hair growth.

This study observed that the compound EM-402 reduced 5α-reductase activity and sebaceous gland size in the flank organs and ears of hamsters, indicating potent localized anti-androgenic effects without systemic action.

This study found that olorofim demonstrated potent in vitro and in vivo antifungal activity against dermatophytes, resolving skin lesions in a guinea pig model similar to clotrimazole, suggesting it may be a promising treatment for dermatophytosis.

This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.

This study identified a novel SCF mRNA splice variant in white merino sheep skin, which may play a role in hair follicle melanogenesis.

This study identified key proteins, FKBP10 and FBN2, that promote the growth cycle of secondary hair follicles in cashmere goats, with higher expression in the anagen phase, offering insights into mechanisms potentially enhancing cashmere yield and quality.

This study developed a novel ferritin-based delivery system (LR@Fn) that effectively co-delivers RG108 and LLY283 for hearing loss treatment in animal models, reducing hair cell loss and synaptic damage more effectively than dexamethasone.

This report describes effective treatment of demodicosis in ferrets using amitraz, marking the first known cases in this species.

This study found that eflornithine 15% cream reduced unwanted facial hair growth more effectively than a placebo in women with hirsutism, but hair growth returned to pretreatment levels within 8 weeks of stopping treatment.

Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.

This study demonstrated that CEP may effectively treat pulmonary fibrosis by inhibiting fibroblast activation through regulating macrophage M2 polarization and decreasing fibrosis-associated factors, suggesting a new avenue for future research in this area.

In this study, fibroblasts treated with the small molecule peficitinib were reprogrammed into dermal papilla cell-like cells capable of inducing hair growth, offering a new strategy for hair loss treatment.

This study reports that taxifolin from enzymatic hydrolysis effectively regulates dermal papilla cell apoptosis and promotes hair growth by increasing IGF-1 and reducing TGF-β1, though it shows less inhibition of DHT compared to minoxidil.