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Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.

Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Some skin medications are safe for pregnant women, but others pose risks or should not be used.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Patients with metabolic syndrome often have skin problems like acanthosis nigricans and skin tags, and early treatment is important to prevent serious issues.

Skin infections and eczema were most common in all ages, acne in teens and young adults, and nutritional skin problems and infestations in children.

Skin symptoms can indicate endocrine disorders and have various treatments.

Alopecia linked to higher anxiety and personality disorders.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

New treatments for skin and hair disorders in women of color address unique biological differences and include specific acne medications, sunscreens, skin lighteners, and hair care adjustments.

Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.

Fish oil improves skin health in people with diabetes and high cholesterol.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.