26 citations
,
August 2016 in “ACS Applied Materials & Interfaces” In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.
This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.
15 citations
,
July 2004 in “Journal of morphology” This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.
30 citations
,
November 2012 in “Proceedings of the Royal Society B Biological Sciences” This study found that the keratin matrix in mammalian hard α-keratins is crucial for maintaining stiffness in water by controlling intermediate filament hydration.
April 2018 in “Journal of Investigative Dermatology” This study found that keratin filament networks in SG1 cells of mice undergo dynamic changes during cornification, impacting the barrier function of the stratum corneum.
40 citations
,
March 1991 in “Journal of Investigative Dermatology”
16 citations
,
July 2015 in “Journal of Molecular Structure” This study comprehensively compared different crystalline forms of finasteride, including the new finasteride DMF solvate hemihydrate, to better understand their structural characteristics and intermolecular interactions.
1 citations
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December 2022 in “Applied Sciences”
7 citations
,
December 2011 in “Annals of anatomy” This study found that involucrin likely plays a key role in forming the cornified material of the medulla and inner root sheath of human hair, contributing to its mechanical strength.
36 citations
,
January 1994 in “Cell and Tissue Research” 5 citations
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September 2024 in “Life” Natural products can safely and effectively treat various human diseases.
August 2025 in “Andrology” In this study, the researchers reconstructed Abraham's family pedigree from the Bible's book of Genesis to explore potential medical or genetic explanations for reported cases of familial infertility, linking historical accounts with plausible scientific reasoning.
86 citations
,
April 2009 in “Journal of anatomy” This paper reviews the evolution of skin appendages and keratin-associated proteins among amniotes, proposing a model for their genetic divergence without new experimental results.
17 citations
,
August 2014 in “The Anatomical Record” The researchers reported that scaffoldin, a protein identified in chicken embryos, likely plays a role in forming periderm granules and contributes to the soft cornification of embryonic epidermis.
20 citations
,
December 2010 in “Journal of Morphology” In this study, researchers found that alpha-keratin homologs similar to those in mammalian hair are present in the claws of the lizard Anolis carolinensis, suggesting a structural role during claw formation.
4 citations
,
October 2018 in “Skin appendage disorders” This article reviews the pros and cons of co-washing for hair cleansing and presents no new clinical results; the authors describe potential residue buildup as a drawback.
October 2014 in “Microscopy” This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.
1 citations
,
November 2023 in “Cosmetics” This study found that washing hair with surfactants reduces the internal density of hair due to cuticle lifting, and suggests that a cuticle-sealing strategy can inhibit this effect and maintain hair homeostasis.
15 citations
,
July 2019 in “Journal of Biological Inorganic Chemistry” This study found that finasteride effectively prevented testosterone-induced kidney stone formation in renal tubular cells by reducing COM crystal adhesion and crystallization.
7 citations
,
July 2014 in “BMJ case reports” This article reviews the rare skin disorder ichthyosis with confetti, highlighting the potential for future therapies using revertant stem cells, and reports no new clinical results.
November 2025 in “ACS Omega” This study found that incorporating Canavalia ensiformis lectin into alginate and carboxymethylcellulose films enhanced angiogenic factor expression, suggesting these biopolymer films could be an effective alternative for wound treatment.
2 citations
,
December 1994 in “International Journal of Cosmetic Science” In this study, the combination of biologically engineered hyaluronic acid and polyquaternium-10 improved hyaluronic acid's retention and moisturizing effects on hair by forming a stable complex that increased binding affinity to keratin.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.
73 citations
,
January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
6 citations
,
June 1976 in “Journal of ultrastructure research” This study identified the presence of recognizable organelles, such as lysosomes and mitochondria, in both the keratinized fiber and the hardened inner root sheath of the Romney wool follicle.
8 citations
,
July 2014 in “American Journal of Dermatopathology” This discussion reviews the classification and naming of cutaneous cysts, proposing that cysts typically named cutaneous keratocyst and steatocystoma should be unified under the term "sebaceous duct cyst," but it reports no new clinical results.
This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.
March 2026 in “Dermatology Online Journal” In this case report, the authors describe a rare cystic panfolliculoma in an 84-year-old man's right conchal bowl, noting its potential to mimic other tumors like basal cell carcinoma, which complicates diagnosis.
30 citations
,
April 2017 in “Journal of structural biology” This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.
14 citations
,
April 1976 in “Journal of Cutaneous Pathology” This case report observed a subepidermal calcified nodule on the face of a 15-year-old boy, thought to originate from hair follicles, with calcium being eliminated through the skin.