99 citations
,
October 2008 in “Journal of Investigative Dermatology” This study identified genetic mutations linked to congenital ichthyosis in families from the UAE and Turkey, revealing a connection between keratinization disorders and impaired filaggrin processing.
85 citations
,
April 2007 in “Dermatologic Clinics” This article reviews drug-induced hair changes, highlighting that while many drugs are occasionally linked to hair loss, this connection has been conclusively established for only a few, and such hair loss is typically reversible.
64 citations
,
March 2017 in “Nature communications” This study identified 63 genetic loci associated with male-pattern baldness, uncovering genes and pathways that may help develop treatments and suggesting its connection to other human conditions.
61 citations
,
August 1993 in “PubMed” This study found that solid basal cell epitheliomas and the outer root sheath of human hair follicles display nearly identical cytokeratin profiles, suggesting a potential origin connection.
58 citations
,
November 1969 in “British Journal of Dermatology” This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.
56 citations
,
March 2015 in “Cell death and differentiation” This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.
55 citations
,
March 2010 in “Aging” This study found that circadian clock genes are involved in regulating the hair growth cycle, suggesting a connection between daily rhythms and the longer hair follicle cycling process.
32 citations
,
December 1969 in “The Lancet” This study found a significant shift to the telogen phase in the hair growth of children with classical marasmus compared to normal children, suggesting a connection to the chronicity of the condition.
26 citations
,
December 2015 in “International Journal of Dermatology” This abstract reviews the symptom of trichodynia, a painful scalp sensation linked to hair loss, and highlights its potential connection to inflammation but reports no new research findings.
23 citations
,
March 2016 in “American Journal of Primatology” This study found that female rhesus macaques who gained hair showed a significant reduction in hair cortisol concentrations, suggesting a connection between hair regrowth and stress levels.
23 citations
,
April 1993 in “Gastroenterology” This study reported a case where cyclosporine treatment in a child led to remission of ulcerative colitis and regrowth of scalp and body hair, suggesting a possible connection between the disorders.
14 citations
,
July 2019 in “Journal of Investigative Dermatology” In this study, targeted inactivation of the integrin-linked kinase gene in melanoblasts led to defects in cell migration, proliferation, and ability to populate the skin, implicating an integrin-linked kinase-Rac1 connection in melanocyte function.
13 citations
,
February 1980 in “Journal of Cutaneous Pathology” This study observed that seborrheic keratosis lesions in five patients exhibited specific histological changes after trauma, suggesting a connection between these lesions and hair follicle structures.
12 citations
,
November 2024 in “Journal of Ovarian Research” This study found that interleukin-1-alpha and oncostatin-M levels were positively associated with PCOS development, while interleukin-7, IL15RA, and CXCL11 were negatively associated, suggesting a connection between inflammatory factors and PCOS.
8 citations
,
February 2022 in “Frontiers in Medicine” This article reports a case of Rowell syndrome in a woman with chronic cutaneous lupus erythematosus that appeared to be triggered by COVID-19 infection, suggesting a potential connection.
6 citations
,
October 2024 in “BMC Infectious Diseases” This study observed that COVID-19 patients in Thailand infected with the Delta variant were more likely to develop pneumonia and certain post-infection conditions, while Omicron infections were associated with milder symptoms like sore throat and congestion.
5 citations
,
October 2013 in “Experimental Dermatology” This study observed that putrescine and HR form a negative feedback mechanism affecting hair cycling, indicating a significant connection between HR, polyamines, and hair growth regulation.
3 citations
,
January 2022 in “JAAD Case Reports” This article reports a unique case of a 60-year-old woman with alopecia areata and myasthenia gravis, suggesting a rare paraneoplastic syndrome connection primarily limited to prior reports involving hematologic cancers.
3 citations
,
May 2018 in “The American Journal of Medicine” This case report describes a 33-year-old woman with long-standing scalp issues and hair loss, revealing an unusual connection to past melanoma, but it presents no new research results.
3 citations
,
January 2011 in “American Journal of Hematology” This study describes a case where immunochemotherapy, including chlorambucil and rituximab, successfully reversed agranulocytosis and other Waldenström's macroglobulinemia symptoms, indicating a possible connection between the two.
2 citations
,
March 2023 in “Zenodo (CERN European Organization for Nuclear Research)” The researchers reported three cases where systemic lupus erythematosus appeared 4-6 weeks after mild COVID-19 in women, suggesting further studies are needed to explore this potential connection.
2 citations
,
April 2010 in “The Open Dermatology Journal” This review discusses the development and role of corneodesmosin in skin and hair follicle integrity, highlighting findings from mouse models and its connection to genetic diseases, with no new experimental results included.
1 citations
,
January 2025 in “Neuropsychopharmacology Reports” In this study, researchers found a direct link between autism and the intake of sugar and maltose, while an inverse connection was observed with the intake of total carbohydrate, fructose, and lactose, indicating a potential relationship between dietary patterns and autism.
1 citations
,
June 2014 in “International Journal of Dermatology” This correspondence discusses follicular mucinosis in association with pregnancy but does not report new clinical results, instead calling attention to the observed connection.
1 citations
,
June 1942 in “JAMA” This article discusses observations about the relationship between baldness and gray hair in middle-aged men, noting that baldness often precedes grayness, and suggests a possible connection to premature aging, but reports no new data.
January 2026 in “Neurochemistry International” This study reports that in human glioblastoma and neuroblastoma cell lines, 24-hydroxycholesterol significantly suppressed the conversion of testosterone to growth-inducing androgens via the 5α-reductase pathway, revealing a new connection between cholesterol homeostasis and androgen metabolism.
January 2026 in “SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital” This study highlights that progressive hair loss, like androgenetic alopecia in males, is linked to negative psychosocial and psychosexual effects, including potential sexual dysfunction and diminished self-esteem, but few studies have specifically addressed the connection between sexual health and psychological issues in these patients.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, low serum calcium and dietary incompatibilities were linked to hair loss, supporting Ayurveda's connection between Asthi Dhatu and hair, and suggesting an integrative approach for prevention.
September 2025 in “International Journal of Cosmetic Science” This study found that for straight hair, friction mainly influences fragment formation during combing, suggesting no direct connection to tensile fatigue failure, while with textured hair, combing performance may be more complex.
September 2025 in “PubMed” This study explores Unani and modern medical perspectives on hirsutism, highlighting similarities in their understanding of its connection with amenorrhea and hyperandrogenism, and suggests further integrative research.