research Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative Anti-Androgen Cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
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research Anti-Androgenic Curcumin Analogues as Steroid 5-Alpha Reductase Inhibitors
Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors and Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.
research Determination of Rat 5α-Reductase Type 1 Isozyme Activity and Its Inhibition by Novel Steroidal Oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research New Insights into the Research of Bioactive Compounds from Plant Origins with Nutraceutical and Pharmaceutical Potential
Plant bioactive compounds are important for health and can help prevent various diseases.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Integrated Chemometric Fingerprints of Antioxidant Activities and HPLC-DAD-CL for Assessing the Quality of the Processed Roots of Polygonum Multiflorum Thunb. (Heshouwu)
The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.
research Ethosomes in Hair Dye Products as Carriers of the Major Compounds of Black Tea Extracts
Ethosomes improve black tea extract absorption in hair dye.
research GC-MS Analysis and Phytochemical Screening of Indigofera Tinctoria Leaf Extract Characterizing Its Medicinal Use
Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.
research Quantitative Determination of Nutraceuticals in Matured Unripe Fruits of Three Edible Musa Species Using GC-MS
Unripe fruits of three banana species have many health-boosting compounds useful for medicine.
research Medicinal Plants in Nutricosmetics
Medicinal plants in nutricosmetics contain compounds that can improve skin and hair health.
research Ethnopharmacological Significance of Eclipta Alba (L.) Hassk. (Asteraceae)
Eclipta alba has many health benefits and contains compounds with potential for drug development.
research Perilla Frutescens: A Rich Source of Pharmacologically Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Organic and Biogenic Nanocarriers as Bio-Friendly Systems for Bioactive Compounds Delivery: State-of-the-Art and Challenges
Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
research A Comprehensive Review on Deep Eutectic Solvents and Their Use to Extract Bioactive Compounds of Pharmaceutical Interest
Deep eutectic solvents are eco-friendly and effective for extracting useful pharmaceutical compounds.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Elicitor Mediated Enhancement of Wedelolactone in Cell Suspension Culture of Eclipta Alba (L.) Hassk
Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
research Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft
Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.
research Androgenetic Alopecia: Overview
AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
research Placental Extracts, Proteins, and Hydrolyzed Proteins as Active Ingredients in Cosmetic Preparations for Hair Loss: A Systematic Review of Available Clinical Evidence
Placenta products might help with hair loss, but more research is needed.
research Plants Used in Cosmetics
Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
research Dermocosmetic Aspects of Hair and Scalp
New hair products are being developed to keep hair and scalp healthy for everyone.
research Hair Conditioners: Impact of Oral Supplements on Skin and Hair Health
Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Semecarpus Anacardium Linn.: A Review
Semecarpus anacardium Linn. has many medicinal benefits.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research A Potential Review of Its Traditional Uses, Phytochemistry, Pharmacology, and Toxicity of Plumbago Zeylanica
Plumbago zeylanica has valuable medicinal properties but needs sustainable cultivation methods.
research Self-Assessment: Case Studies on Skin Conditions and the Importance of Sun Protection and Skin Examinations
Early detection and skin biopsies are crucial for treating skin cancer and diagnosing various skin conditions.