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Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Men's thigh hair grows longer and has a longer growth cycle than women's, but arm hair growth is similar between genders.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Mycophenolate mofetil was effective for most patients in treating scarring hair loss, but some had side effects.

Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Alopecia areata is an unpredictable autoimmune hair loss condition, treated based on severity, with half of patients regrowing hair within a year without treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The VQ-Dermato is a reliable French questionnaire for measuring quality of life in chronic skin disorder patients.

Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.