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Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

PCOS is a common hormonal disorder in women that can lead to serious health problems.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.

Middle-aged women with PCOS often continue to experience symptoms related to high androgen levels, like unwanted hair growth.

Bicalutamide may help treat female pattern hair loss.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.