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Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.

In this laboratory study, the researchers found that combining dermal papilla cell-derived exosomes with collagenous sequences significantly enhanced hair follicle stem cell migration and proliferation, highlighting a potential strategy for hair regeneration through modulation of the hsa-novel-238a-CASP9 axis.

This case report identifies collagenous gastritis as the cause of chronic gastrointestinal symptoms in a 27-year-old male, characterized by severe chronic inactive gastritis and a distinctive subepithelial collagen band.

This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.

This study reported that bioactive peptides from skin collagen, obtained through selective hydrolysis, improve skin collagen synthesis and remodeling, while inhibiting its breakdown by metalloproteinases, showing benefits such as enhanced skin hydration, elasticity, healing, and hair restoration, without associated adverse effects.

This study found that permanent wave lotion I extracts proteins from human hair, with molecular weights ranging from 5,000 to 65,000, which may elucidate hair damage mechanisms.

This review highlights encouraging findings on platelet-rich plasma's effectiveness in improving skin texture, firmness, and elasticity in aesthetic procedures but emphasizes the need for more standardized protocols and robust clinical trials.

This study found that basal cell epithelioma resembles fetal primary epithelial germ based on specific cellular characteristics.

This case study documented a black male newborn developing large bullae that healed with hypopigmentation, suspecting proteolytic enzymes in keratinocytes caused the collagenolysis responsible for the condition.

This case report concludes that the presence of distinctive histiocytic responses in a Cambodian woman's eyelid lipogranulomas suggests surreptitious silicone injections despite her denial of prior procedures.

Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.

In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.

In this study, researchers examined the skin of neonatal rabbits and found that most hair follicles were in the terminal stage, with hair shafts protruding through the epidermis, but noted the absence of sweat glands.

In this study, the researchers reported the detailed anatomical structure of horse skin, including the composition and organization of the epidermis, dermis, and associated glands and follicles.

This histological study of Millivora Capenesis skin describes the composition of the dermis, featuring distinct papillary and reticular layers with associated structures like hair follicles, glands, and corpuscles.

This article highlights the importance of early diagnosis and management of certain cutaneous adverse drug reactions and autoimmune disorders in dermatological emergencies, but it reports no new clinical results.

This study found that human hair keratin can serve as a matrix for skin structure restoration, as observed in rats where the graft was replaced by newly formed collagenous fibers over six weeks.

Acquired perforating dermatosis often affects skin in people with kidney issues and diabetes.

This case report describes a black male newborn who developed bullae that healed with hypopigmentation, linked to collagenolysis and RER vacuoles potentially containing proteolytic enzymes.

Canine skin has two main layers: the epidermis and dermis, with a supportive subcutis layer.

This report describes cases of trichoblastoma and trichoepithelioma in mixed-breed dogs, highlighting their distinct microscopic characteristics without suggesting broader clinical implications.

In this animal study, researchers observed that both aging and lower androgen levels in male albino rats led to significant structural changes in meibomian glands, including reduced acinar cell size, diminished meibum secretion, and increased collagen deposition.

This review found that hydrolyzed collagen supplementation, particularly marine collagen, improves skin hydration, elasticity, and density while strengthening hair and nails, especially when paired with vitamin C and trace elements; however, more studies are necessary to evaluate long-term efficacy across different sources and demographics.

This chapter discusses various aspects of collagen, proposing "extended collagen carential disease" as a new concept tied to nutritional deficiencies, notably Vitamin C's role in maintaining collagen health.

This review reports that collagen peptides provide consistent, modest benefits for skin hydration and elasticity, with variable effects on body composition and cardiometabolic risk markers, though some outcomes remain inconsistent due to trial heterogeneity.

This review reports that collagen peptides consistently provide modest improvements in skin hydration and elasticity and varying benefits for body composition and cardiometabolic markers, although effects on blood sugar control are less consistent; variations in source, dose, and study definitions limit generalizability.

In this study, researchers identified a collagen fragment, sample-1707, expressed in E. coli, which forms nanofibers and promotes blood clotting, osteoblast differentiation, and skin cell regeneration, making it a promising biomaterial for skin care, with a large-scale production yield of 600 mg/L.

This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.

This animal study found that transparent porcine-derived Type I atelocollagen increases skin thickness and regenerates elastic fibers in aged mice, suggesting its potential as a skin booster for rejuvenation.

This review examined the use of platelet-rich plasma in aesthetic skin rejuvenation and found promising results when combined with other treatments, but limited efficacy when used alone.