Acquired Perforating Dermatosis in Renal and Diabetic Patients
March 1997
in “
The Lancet
”
TLDR Acquired perforating dermatosis often affects skin in people with kidney issues and diabetes.
The document discussed acquired perforating dermatosis, a condition affecting the skin, particularly in patients with renal issues and diabetes. It highlighted the complexity of dermal-epidermal interactions and identified four primary perforating dermatoses: Kyrle's disease, perforating folliculitis, reactive perforating collagenosis, and elastosis perforans serpiginosa. These conditions are characterized by transepidermal elimination, where materials like keratin, collagen, or elastin are expelled through the epidermis. The document emphasized the histological features and potential pathogenesis of these conditions, particularly in the context of diabetes and renal failure.
