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Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.

The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Latanoprost can make eyelashes longer, thicker, and darker.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Certain gene variations may increase the risk and severity of alopecia areata.

The symposium concluded that environmental factors significantly contribute to skin aging.

Removing part of the vitamin D receptor stops vitamin D from working properly.

No treatment fully prevents hair loss from chemotherapy yet.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

Cell aging can be both good and bad for tissue repair.