2 citations
,
September 2009 in “Hormone Molecular Biology and Clinical Investigation” This study found that low-dose finasteride treatment in men with premature androgenetic alopecia decreased levels of 5α-reduced steroids, which may be linked to increased depression symptoms.
April 2026 in “BMC Biotechnology” This study found that curcumin spanlastics demonstrated greater antimicrobial, antioxidant, and anticancer activities in the MCF-7 breast cancer cell line compared to curcumin alone or curcumin nanocrystals, also affecting several cancer-related protein markers and showing enhanced solubility and activity.
25 citations
,
July 2024 in “Frontiers in Pharmacology” Gepant medications for migraines show varied safety profiles in this study, with specific adverse events reported across systems like gastrointestinal and skin disorders, highlighting the need for tailored treatment and monitoring.
24 citations
,
May 2016 in “Stem Cell Reviews and Reports” This article reviews the roles and mechanisms of stem and progenitor cell migration in adult organs for tissue homeostasis and regenerative medicine, but reports no new experimental results.
6 citations
,
August 2023 in “Journal of Investigative Dermatology” This study investigated how keratinocytes in the skin respond to different iron levels and found they play a significant role in regulating iron homeostasis by storing iron, affecting epidermal differentiation, and influencing inflammation-related gene expression in mice.
2 citations
,
November 2013 in “Elsevier eBooks” This chapter discusses the role of hormones in regulating reproductive biology and outlines how the endocrine system, particularly the brain and pituitary gland, controls these hormonal processes.
January 2013 in “The Journal of Sexual Medicine” In a rat model, this study found that a hydrogel incorporating adipose-derived stem cells and nerve growth factor may aid in the recovery of erectile function following cavernous nerve injury.
December 2025 in “Journal of Cosmetic Dermatology” This systematic review found that intralesional dutasteride treatments for androgenic alopecia in adults improved hair density and thickness with minimal adverse effects, although study methodologies varied and lacked large-scale trials.
May 2023 in “Journal of Cosmetic Dermatology” This study found that AGA patients had higher serum and epidermal irisin levels, which were associated with metabolic syndrome, dyslipidemia, and abnormal carotid intima media thickness, suggesting potential irisin resistance affecting cardiometabolic health.
233 citations
,
November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores androgen metabolism in the skin, highlighting enzyme localization and potential implications for treating androgen-dependent skin conditions, but it reports no new clinical results.
71 citations
,
May 2019 in “Rheumatology” This study observed that PD-1+CXCR5-CD4+T peripheral helper cells are significantly elevated in patients with systemic lupus erythematosus and are correlated with disease activity indicators, suggesting their potential role in lupus pathogenesis.
60 citations
,
January 2023 in “Biogerontology” This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.
51 citations
,
October 1981 in “British Journal of Dermatology” This study found that in patients who underwent jejuno-ileal bypass for morbid obesity, dapsone was effective in treating inflammatory skin lesions and joint symptoms when other antibiotics failed.
50 citations
,
November 2020 in “Physiology & behavior” This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.
37 citations
,
February 2023 in “Gut Microbes” This study found that administering the gut bacterium Thauera sp. strain GDN1 to mice significantly reduced their serum androgen levels, indicating gut bacteria may influence androgen metabolism.
23 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses rodent models of alopecia areata and suggests they are crucial for understanding the autoimmune mechanisms and potential treatments but reports no new clinical results.
13 citations
,
December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” This review discusses the potential of follicular drug delivery systems to target the pilosebaceous unit and reports no new research findings.
2 citations
,
September 2024 in “Journal of the American Academy of Dermatology” Higher monocyte counts may predict poor response to adalimumab in hidradenitis suppurativa patients.
2 citations
,
November 2015 in “Journal of Investigative Dermatology” This study found that RANKL signaling enhances CD8+ T cell-mediated anti-viral immunity during herpes simplex virus infection by preventing apoptosis of Langerhans cells, suggesting potential therapeutic applications.
1 citations
,
March 2017 in “Al-maǧallaẗ al-’irāqiyyaẗ li-l-’ulūm al-ṣaydalāniyyaẗ/Iraqi journal of pharmaceutical sciences” This study suggests that using nutrient antioxidants can significantly reduce the dose of prednisolone needed in alopecia areata patients while potentially enhancing hair growth and mitigating side effects.
August 2026 in “Cell Biomaterials” D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.
February 2025 in “International Journal of Molecular Sciences” This meta-analysis of animal studies found that alkaloids have potential anti-influenza and anti-inflammatory effects, correlating with improved viral titers and survival rates, though they did not effectively reduce TNF-α and IL-6 levels. Extensive further studies are needed to confirm these findings before considering clinical application.
November 2024 in “Journal of Investigative Dermatology” Certain NK cell changes in blood may indicate alopecia areata progression.
March 2024 in “Journal of clinical medicine” This study examined trichoscopic findings in androgenetic alopecia, reporting that hair diameter variability, vellus hairs, and the peripilar sign are valuable indicators for diagnosing this condition.
3 citations
,
April 2016 in “Wound Repair and Regeneration” In this study, researchers developed a new murine model for transplanting vibrissae that mimics human hair transplantation, achieving successful hair growth in immune-deficient nude mice.
25 citations
,
August 2015 in “Journal of cosmetic dermatology” This study observed significant differences in hair care practices and biologic hair parameters between Caucasian and African American women, which may contribute to varying hair fragility and growth.
8 citations
,
January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that Cinobufacin combined with chemotherapy improved clinical outcomes in breast cancer patients and reduced certain side effects compared to chemotherapy alone.
3 citations
,
December 2021 in “Acta dermato-venereologica” This meta-analysis found that patients with androgenetic alopecia had a significantly higher prevalence of metabolic syndrome and poorer metabolic profiles compared to controls, especially among females, those with early onset, and individuals of African ethnicity.
1 citations
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January 2025 in “Dermatology Practical & Conceptual” This review describes trichoscopy features of lichen planopilaris and frontal fibrosing alopecia, identifying distinct patterns that help differentiate the two conditions.