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The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

DNA methylation changes are linked to hair growth cycles in goats.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Dutasteride is more efficient than finasteride, but individual results vary.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The document concludes that more research is needed to fully understand the causes of PCOS.

Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.

Men with more vanadium in their blood and who drink less soy milk are more likely to have hair loss.

Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.

Women who had bariatric surgery risk nutritional deficiencies causing skin issues during pregnancy and breastfeeding.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.

Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.