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The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

New treatments targeting specific genes show promise for treating keratin disorders.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Alopecia areata can cause unpredictable hair loss, and treatments like corticosteroids and minoxidil may help but have varying side effects.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Hair loss in women may have causes other than hormones.

DHT, a testosterone byproduct, causes male pattern baldness.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.