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Activating the Sonic hedgehog gene in mice can start the hair growth phase.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Oral zinc therapy is effective for treating acrodermatitis enteropathica.

Terbinafine can cause hair loss.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

Cyclosporin doesn't stop hair loss.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

New treatments for male hypogonadism are effective and should be personalized.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

DHT, a testosterone byproduct, causes male pattern baldness.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

Quick treatment of hair disorders in teenage girls is important because of the emotional effects.

Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.