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Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Dunaliella salina microalgae is safe to eat and may boost health.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hair growth and development are controlled by specific signaling pathways.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.

Chromosomal microarray analysis is important for diagnosing rare genetic variations and guiding treatment.

Chromosomal differences affect how muscle cells respond to testosterone.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

People with Down's syndrome are more likely to have syringomas.

A baby girl had two brain-related growths removed and is developing normally.

Melatonin can help prevent and treat skin damage caused by gamma rays.

A patient with Rothmund-Thomson syndrome showed skin changes, hair loss, and dental defects but no cataracts or skeletal issues.

A hospital outbreak of catheter infections in calves was caused by a bacteria from a beef herd, leading to longer hospital stays, more drug use, and calf deaths.