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Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Melatonin may reduce skin damage caused by X-rays in rats.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Genes and hormones cause hair loss, with four genes contributing equally.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Polyamines help fix DNA damage accurately in cells.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

New genes found linked to balding, may help develop future treatments.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

FLRG and follistatin have different roles in wound healing.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.