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Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.

Minoxidil mixed with 2-hydroxypropyl-β-cyclodextrin in water can improve hair growth more than minoxidil alone.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Low-level laser therapy improves hair growth and dermal papilla cell function.

Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.

The essential oil from Chamaecyparis lawsoniana has strong antibacterial and antifungal effects, especially against yeast and Gram-positive bacteria.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.

The herbal hair oil effectively promotes hair growth, nourishes the scalp, and prevents dandruff.

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

Smoking and drinking can lower vitamin levels and potentially trigger early hair loss, but overall vitamin levels don't seem to affect hair loss duration.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Sebocytes play a key role in controlling androgen levels in human skin.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.