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Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

People with hair loss have worse cholesterol levels, possibly linking hair loss to heart problems.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.

Gene mutations can cause problems in male genital development.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.