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300-330 / 1000+ resultsresearch Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract
This study found that shallot extract may promote hair growth in androgenetic alopecia by reducing inflammation and modulating gene expression related to key hair growth pathways.
research Editorial Note on Next-Generation Therapies and Advance Acne Treatment
This study reported that clascoterone cream reduced inflammatory and noninflammatory acne lesions in a trial with 1440 white males and non-pregnant females, showing it was well tolerated in these participants.
research Abstract P1-09-32: A novel candidate for chemotherapy induced alopecia (CIA) through local modulation of apoptosis and inflammation
This study found that a new treatment candidate may effectively prevent and promote recovery from chemotherapy-induced alopecia by normalizing apoptosis and reducing inflammation in cancer patients.
research Ethinylestradiol/Chlormadinone Acetate for Use in Dermatological Disorders
This case series suggests that EE/CMA 0.03mg/2mg may help manage dermatological disorders related to androgen excess, as evidenced by symptomatic improvements in the four patients treated.
research Do Syrian conflict survivors show novel chronic cutaneous sequelae from chlorine gas exposure: A case report and literature review
In this case study, researchers documented chronic dermatitis and ulcerative lesions in a 70-year-old Syrian man following chlorine gas exposure during the conflict, highlighting the need for healthcare planning and registries to manage long-term effects in affected populations.
research Case of Cronkhite Canada syndrome shows improvement with enteral supplements.
This case report describes a 33-year-old Indian male with Cronkhite-Canada syndrome who experienced complete symptom recovery within 5 months after starting a high protein diet, proton pump inhibitors, and zinc-vitamin supplements.
research Cosmetics and Cosmeceutical Applications of Chitin, Chitosan and Their Derivatives
This review examines the roles and benefits of chitosan in cosmetics and oral hygiene, highlighting its potential in the cosmeceutical market, but it reports no new results.
research Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
This study found that formulations containing saccharide isomerate significantly improved scalp flaking, sebum secretion, and transepidermal water loss compared to placebo in an adult Chinese population with dandruff.
research New agents for cancer chemoprevention
This article discusses ongoing and planned clinical chemoprevention trials for various agents and combinations but reports no new results; it highlights promising new agents and the evolving focus on molecular pathways.
research 加齢性白質病変(leukoaraiosis)update (特集 あしたの脳梗塞)
This study found that saponin derivatives from P chinensis may effectively block CRH receptor function and could be used to treat stress-induced hair loss.
research Citrullus colocynthis (L.) Schrad. (Cucurbitaceae)
research Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia
The authors concluded that plasma levels of 3α-diolG, ADTG, and DHTG in women with hyperandrogenic disorders primarily reflect adrenal androgen contributions rather than peripheral action, suggesting a potential index for treatment effectiveness.
research Abstract 5122: A novel topical candidate for chemotherapy and radiotherapy-induced alopecia (CRIA) through local modulation of apoptosis
This study observed that applying a GMP-grade botanical extract to the scalp increased Bcl-2 levels, potentially preventing premature hair follicle apoptosis in chemotherapy and radiotherapy-induced alopecia.
research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro, and In Silico Studies
This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.
research Calcitriol and Alopecia—Is it the Hair Apparent?
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
This study found that antroquinonol inhibited CD8+ T cell proliferation and reduced proinflammatory cytokine secretion in vitro, while also ameliorating H2O2-induced depigmentation and resisting reductions in hair follicle length, skin thickness, and tyrosinase expression in mice.
research Diffuse Gastrointestinal Polyposis With Skin, Hair, and Nail Changes
This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.
research Prospective Efficacy and Safety Study of an Innovative Kerascalp Hair Growth Serum in Mild-to-Moderate Alopecia in India: Regrowth Study
In this open-label study, the researchers observed that using Kerascalp hair serum daily for 90 days improved hair thickness, density, and strength while reducing hair loss in subjects with mild to moderate androgenetic alopecia, with benefits persisting even after discontinuation.
research Suspected Calcinosis Cutis and Demodicosis, Secondary to an Exogenous Steroid Administration in a Dog with Hypoadrenocorticism
This case study reported that reducing glucocorticoids resolved calcinosis cutis in a dog with hypoadrenocorticism, while demodicosis was treated with a fluralaner chewable tablet.
research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists
This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.
research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
This study found that novel androgen antagonists incorporating a carborane moiety showed anti-androgenic activity comparable to flutamide in a laboratory setting.
research Real-World Experience of Clascoterone Cream 1% in Acne Management: Case Series and Canadian Experience
This case series involving 10 patients treated with clascoterone cream 1% for acne vulgaris found it effective and well-tolerated, regardless of severity, age, gender, or ethnicity, and noted additional benefits for related skin conditions.
research Iatrogenic Cushing's Syndrome in a Patient With Salt-Wasting Congenital Adrenal Hyperplasia (SWCAH)
This case report of a 17-year-old with salt-wasting congenital adrenal hyperplasia due to 21-hydroxylase deficiency found that increasing the mineralocorticoid dose relieved daily headaches and reduced salt cravings.
research Synthesis of avicequinone c and analogs toward the study of 5α-reductase inhibitory activity
This study found that 2-hydroxy-1,4-naphthoquinone was the most effective inhibitor of steroid 5α-reductase, showing stronger inhibition than avicequinone C in HaCaT cell assays.
research A Case of Cronkhite-Canada Syndrome Presenting with Hematochezia
This article reports on a patient case of Cronkhite-Canada syndrome, detailing symptoms and diagnostic findings, and reviews the syndrome's characteristics without presenting new clinical data.
research A review on therapeutic effect of Siddha classical formulation Seenthil Chooranam
This review found that Seenthil Chooranam, a traditional Siddha formulation, has potential therapeutic benefits for various diseases due to its pharmacological properties and bioactive compounds, though further research is needed to confirm its safety and clinical effectiveness.
research A Solitary Firm Nodule Over Cheek
In this case report, a benign trichoadenoma was identified in a 42-year-old man as a skin-colored nodule on the cheek, with histopathology confirming the diagnosis and differentiating it from similar conditions like pilomatricoma and sebaceous cyst.
research Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff
This study found that both an anti-dandruff shampoo containing piroctone olamine and climbazole and its combination with a tonic reduced dandruff and inflammation, with the combination showing superior results.
research Application of 2-Chloro-7-Nitrobenzo-2-Oxa-1, 3-Diazol (NBDCL) for Spectrophotometric Determination of Finasteride in Pharmaceutical Formulation
This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.