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This study identified mutations in the SREBF1 gene that impair SREBP1 function, potentially contributing to IFAP syndrome by affecting skin, hair, and eye development.

In this study, a novel liposomal formulation combining caffeine and cafestol significantly enhanced their penetration into human skin layers, with formulation F9 doubling caffeine and greatly increasing cafestol levels in the dermis, suggesting potential for improved topical delivery.

This study observed that the SREBF1 mutation c.1669C>T (p.Arg557Cys) may act as a recurrent hotspot mutation associated with both hereditary mucoepithelial dysplasia and autosomal-dominant ichthyosis follicularis with atrichia and photophobia syndrome, suggesting they may be on the same clinical spectrum.

This study found that fentanyl accumulates differently in mouse hair after systemic administration compared to external loading, suggesting ionizable functionalities of hair influence drug retention from organic solutions.

This study found that the PPARγ modulator NAC-GED-0507-Levo may protect hair follicles from chemotherapy-induced damage, potentially offering a strategy to address irreversible hair loss in cancer patients.

In this study, researchers conducted an exploratory re-analysis of miRNA dysregulation and aging-related target enrichment using publicly available data on female pattern hair loss, comparing 3 FPHL scalp samples to 5 healthy female controls, and emphasized that the findings are preliminary and require further validation.

This review suggests that excessive facial photoprotection could play a role in frontal fibrosing alopecia through a disturbance in immunological balance via the aryl hydrocarbon receptor-kynurenine pathway.

This study found that protein hydrolysates from mealworms, especially those derived using flavourzyme, significantly enhance adipogenic differentiation in 3T3-L1 preadipocytes, suggesting their potential as sustainable ingredients for glycemic control, skin health, and tissue regeneration products.

This case report describes a unique presentation of frontal fibrosing alopecia characterized by a hair loss pattern that resembles the Greek letter upsilon, supported by trichoscopic and histological findings.

This review critically examines Forensic DNA Phenotyping, highlighting high accuracy in predicting certain traits but also legal and ethical challenges, particularly around regulatory fragmentation and issues of genetic privacy.

This study presents cases suggesting that hair transplantation may trigger de novo frontal fibrosing alopecia in some patients, highlighting a potential association worth considering as cosmetic hair procedures become more common.

This study found that lipid accumulation product (LAP) and free androgen index (FAI) can highly predict liver steatosis in women with PCOS phenotype A.

New topical treatments and methods can help manage female pattern hair loss.

This study found that Facia Men’s capsule significantly reduced hair shedding in men with androgenetic alopecia over 12 weeks, without notable renal or liver safety concerns.

This study identified four circulating microRNAs as highly predictive of frontal fibrosing alopecia status, suggesting potential roles in diagnostics and disease understanding.

In this retrospective study, tofacitinib was found to be effective and well-tolerated for treating severe alopecia areata, with 77% of patients achieving a clinical response over 4-20 months, though results were more favorable for patients with less extensive hair loss.

In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.

This pilot study found that examining changes in scalp scales after scraping may effectively distinguish seborrheic dermatitis associated with androgenetic alopecia from fibrosing alopecia in a pattern distribution.

This study found that linoleic acid may help protect against acrylamide toxicity in female albino rats.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

This study identified a novel missense mutation in the FGF5 gene associated with the longhair phenotype in about 3% of Maine Coon cats, suggesting it may be a breed-specific variant.

This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.

In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.

According to this review, frontal fibrosing alopecia in men exhibits unique clinical features and is often misdiagnosed, underscoring the need for validated diagnostic criteria and treatment evaluation.

This case report describes frontal fibrosing alopecia in a woman with primary biliary cirrhosis and polymyalgia rheumatica, suggesting a possible autoimmune link to this form of hair loss.

This study found that concentrated growth factor injections significantly improved hair density, hair follicle density, and hair diameter in 60 patients with androgenic alopecia, with a 93% patient satisfaction rate and no reported complications over a 6-month follow-up period.

In this case report, a 28-year-old male with androgenetic alopecia showed improved hair density and shaft thickness after four monthly sessions of autologous growth factor concentrate injections, with no adverse effects and high patient satisfaction, suggesting the treatment’s promise as a safe and effective option.

In this study, 60.7% of faculty and their family members at Fazaia Ruth Pfau Medical College in Karachi experienced post-COVID symptoms, with no clear link to COVID infection severity.

In this study, researchers used EHR data from two large PCORnet networks to identify a range of long COVID diagnoses, highlighting varying post-acute risks across populations in NYC and Florida.