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Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.

Spermidine helps protect against aging by preserving telomere length.

Quick treatment of hair disorders in teenage girls is important because of the emotional effects.

Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.

Some chemicals absorbed through the skin can cause serious health problems.

Finasteride slows down motherly behavior in first-time pregnant rats.

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

Vogt-Koyanagi-Harada disease can develop during interferon therapy for chronic hepatitis C.

Micro-current stimulation may promote hair growth more effectively than standard treatments.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Propranolol is effective and safe for treating infantile hemangioma, but more research is needed for dosing and monitoring guidelines.

Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Finasteride doesn't affect erections much, but may decrease libido in men.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Cantú syndrome may be linked to pituitary adenomas.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Phenobarbitone can cause severe and sometimes fatal skin reactions.

A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

The PP2A-B55α protein is essential for brain and skin development in embryos.

In a Tuscan pediatric clinic, 7.19% of children had hair or scalp disorders, with nonscarring alopecia being the most common.

Taking Propecia might lead to the development of cataracts.

The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.