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Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.

Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.

The review says skin conditions with sterile pustules need more research for better treatments.

Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.

No clear link between hair loss and metabolic syndrome, but some differences in blood pressure and glucose levels.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.

Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Rivaroxaban can cause liver injury, allergic reactions, blood vessel inflammation, and hair loss, but these side effects are rare.

FUE is a less invasive hair transplant method suitable for many patients, but it has limitations and may not replace traditional techniques.

Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

Platelet-rich plasma therapy could be an effective treatment for melasma with minimal side effects.

Minoxidil can cause deadly skin reaction; monitor patients closely.

Children are at risk of health issues from exposure to platinum group elements from car exhausts.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Oral tofacitinib has a moderate success rate and is generally safe for treating hair loss in some patients.