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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

The virus was not found in the semen and urine of a man who tested positive for COVID-19.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Stem cell niches support, regulate, and coordinate stem cell functions.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.