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    Glossary Cell Microenvironment

    immediate surroundings influencing cell behavior and function

    The cell microenvironment, also known as the cellular microenvironment, refers to the immediate surroundings of a cell, including the extracellular matrix, neighboring cells, and various signaling molecules. This environment plays a crucial role in regulating cell behavior, function, and fate by providing biochemical and mechanical cues. Understanding the cell microenvironment is essential for fields like tissue engineering, cancer research, and regenerative medicine, as it influences processes such as cell growth, differentiation, and migration.

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    1. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    2. Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia PloS one · 2012 · 6 citations
    3. Nanoscale microenvironment engineering for expanding human hair follicle stem cell and revealing their plasticity Journal of Nanobiotechnology · 2021 · 15 citations
    4. Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models BioMed Research International · 2014 · 4 citations
    5. Single‐cell RNA sequencing highlights the role of proinflammatory fibroblasts, vascular endothelial cells, and immune cells in the keloid immune microenvironment International Journal of Dermatology · 2024 · 6 citations
    6. A Consensus Single-cell Atlas Of Hidradenitis Suppurativa Tunnels Defines A Fibro-inflammatory Niche With Druggable Microenvironmental Endotypes Zenodo (CERN European Organization for Nuclear Research) · 2026
    7. A Consensus Single-cell Atlas Of Hidradenitis Suppurativa Tunnels Defines A Fibro-inflammatory Niche With Druggable Microenvironmental Endotypes Zenodo (CERN European Organization for Nuclear Research) · 2026
    8. A Consensus Single-cell Atlas Of Hidradenitis Suppurativa Tunnels Defines A Fibro-inflammatory Niche With Druggable Microenvironmental Endotypes Zenodo (CERN European Organization for Nuclear Research) · 2026
    9. A Consensus Single-cell Atlas Of Hidradenitis Suppurativa Tunnels Defines A Fibro-inflammatory Niche With Druggable Microenvironmental Endotypes Zenodo (CERN European Organization for Nuclear Research) · 2026
    10. Biophysical and Metabolic Cues in the Microenvironment of Skin Wounds: Implications for Stem Cell Behaviour and Epidermal Regeneration MEDS Clinical Medicine · 2026
    11. Regulation of melanocyte stem cell behavior by the niche microenvironment Pigment Cell & Melanoma Research · 2018 · 24 citations
    12. Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time Frontiers in Immunology · 2023 · 5 citations
    13. Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment Development · 2003 · 182 citations
    14. Tolerogenic dendritic cell-conditioned medium promotes hair growth by modulating follicular microenvironment in a DHT-treated mouse model Molecular and Cellular Biochemistry · 2026
    15. A molecular systems architecture of the mesenchymal stromal cell microenvironment Stem Cells · 2025
    16. Fermented Morinda citrifolia extract stimulates hair growth by promoting dermal papilla cell proliferation and modulating the follicular microenvironment Journal of Ethnopharmacology · 2026
    17. Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells Nature · 2010 · 116 citations
    18. A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models BMC Biotechnology · 2026
    19. Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment Journal of Ethnopharmacology · 2024
    20. Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies Journal of Cellular and Molecular Medicine · 2009 · 36 citations
    21. The comparison of the mesenchymal progenitor cell coating state on the MBA and DBM as the biochemical scaffolds Clinical Biochemistry · 2011
    22. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012 · 265 citations
    23. Stem cell dynamics in the hair follicle niche Seminars in Cell & Developmental Biology · 2013 · 135 citations
    24. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging Frontiers in Cell and Developmental Biology · 2022 · 7 citations
    25. Coexistence of a Basal Cell Carcinoma and Leiomyosarcoma: An Unusual Collision Tumor American Journal of Dermatopathology · 2019 · 3 citations
    26. Reporting Live from the Epidermal Stem Cell Compartment! Cell Stem Cell · 2012 · 2 citations
    27. Ni–Cu BimetallicNanozyme and Minoxidil Co-LoadedDissolving Microneedles Reshape Hair Follicle Microenvironment forAndrogenic Alopecia Treatment OPAL (Open@LaTrobe) (La Trobe University) · 2025
    28. Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics International Journal of Molecular Sciences · 2024
    29. Coexistence of a Basal Cell Carcinoma and Leiomyosarcoma American Journal of Dermatopathology · 2019
    30. Scalable and high-throughput production of an injectable platelet-rich plasma (PRP)/cell-laden microcarrier/hydrogel composite system for hair follicle tissue engineering Journal of Nanobiotechnology · 2022