2 citations
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January 2014 in “Hair therapy & transplantation” This review explores the molecular controls of hair follicle cycling and highlights the challenge of developing effective treatments for common hair disorders without providing new clinical results.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that Cannabidivarin (CBDV) promotes neuronal survival, proliferation, and differentiation via TRPV1 activation but inhibits oligodendrocyte differentiation in postnatal neurogenesis.
8 citations
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May 2021 in “Bioengineering & translational medicine” This review examines the challenges of hair follicle regeneration and outlines strategies for bioengineering human hair follicle models, without presenting new experimental results.
55 citations
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April 2015 in “BMC medicine” This study found that the Stem Cell Educator therapy improved hair regrowth and quality of life in patients with severe alopecia areata by restoring immune balance and protecting hair follicles from autoimmune damage.
25 citations
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March 2017 in “Experimental Dermatology” This review discusses various aspects of hair follicle biology and highlights unresolved questions and potential new research avenues, but presents no new experimental findings.
10 citations
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January 2009 in “Elsevier eBooks” This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.
9 citations
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May 2023 in “Stem Cell Research & Therapy” This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.
January 2026 in “Archives of Internal Medicine Research” This review examines how regenerative therapies targeting shared biological pathways can promote healing in musculoskeletal disorders and hair follicle dysfunction, highlighting modalities like platelet-rich plasma and laser therapy while addressing challenges in standardization and measurement.
August 2022 in “Metabolic Brain Disease” In this study with a mouse model of catamenial epilepsy, ferulic acid may effectively reduce seizure susceptibility and depression-like behavior by influencing hormone levels and neurotransmitter activity.
April 2026 in “International Journal of Drug Delivery Technology” This review highlights the various causes and treatment options for alopecia, noting that while non-scarring types often see successful hair regrowth, scarring forms require early intervention to manage inflammatory destruction of hair follicles.
July 2025 in “International Journal of Trichology” This review investigates how various intrinsic factors—such as growth factors, cytokines, chemokines, and interferons—regulate hair growth through evidence gathered from in vitro and in vivo studies, highlighting the need for further research in human subjects to validate these findings.
March 2016 in “Experimental Dermatology” This study reported that EGFR activation leads to suppression of Stathmin, which may promote synchronized entry into catagen in hair follicles, highlighting potential mechanisms involving EGFR in hair cycle transitions.
3 citations
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December 2022 in “npj Regenerative Medicine” This review discusses the role of heparan sulfate proteoglycans in regulating stem cell fate and highlights their potential as targets for addressing hair loss, without reporting new clinical results.
41 citations
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September 1991 in “Medical hypotheses” This article reviews the potential role of prolactin as a neuroendocrine modulator in skin biology and pathology, discussing its relevance for conditions such as psoriasis and hair growth, but reports no new clinical findings.
1 citations
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November 2023 in “iScience” In this study, researchers found that disrupting desmoglein 3 signaling in a mouse model of pemphigus vulgaris activates normally quiescent hair follicle stem cells, compromising their multipotency but prompting a regenerative response that restores stem cell function and structures.
May 2015 in “Cancer Research” This study found that a new treatment candidate may effectively prevent and promote recovery from chemotherapy-induced alopecia by normalizing apoptosis and reducing inflammation in cancer patients.
30 citations
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November 2018 in “EMBO Reports” This study found that the Ovol2-Zeb1 regulatory circuit is crucial for controlling directional migration and proliferation in epithelial cells, facilitating skin regeneration and repair in mice.
42 citations
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July 2012 in “PLOS ONE” This study found that estrogen can cause reversible suppression of the hair cycle by inducing premature catagen and maintaining the telogen phase without damaging the hair follicle stem cell niche or the signature gene expressions of dermal papilla cells.
February 2023 in “International journal of molecular sciences” This study used infrared spectral imaging to show for the first time the distribution of glypican-4 and glypican-6 in hair follicles across different growth phases, highlighting the potential of this technique for studying alopecia.
57 citations
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November 1987 in “Pediatric Dermatology” This article reviews common hair growth abnormalities in children, emphasizing the importance of distinguishing normal development from potential signs of metabolic disorders and indicates no new clinical results.
This study reviews the regulatory mechanisms and molecular processes governing stem cell activity in hair follicles, highlighting their roles in hair regeneration and potential implications for treating hair and skin disorders.
18 citations
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May 2022 in “Stem Cell Research & Therapy” This study found that irradiating human adipose-derived stem cells with green OLEDs enhanced their wound healing capability and increased cell proliferation, migration, and adhesion in preclinical models.
26 citations
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December 1999 in “Journal of Investigative Dermatology” This study found that manipulating prolactin levels in New Zealand Wiltshire sheep induces wool follicle growth cycles, revealing gene expression changes that suggest roles for specific genes in follicle function.
July 2023 in “Biomolecules” In this review, the authors discussed how the circadian clock influences hair follicle regeneration by regulating metabolism, suggesting potential new targets for hair loss treatments.
October 2014 in “Cancer Research” This study observed that applying a GMP-grade botanical extract to the scalp increased Bcl-2 levels, potentially preventing premature hair follicle apoptosis in chemotherapy and radiotherapy-induced alopecia.
October 2022 in “International Journal of Molecular Sciences” This study found that collagen peptides from Mozambique tilapia significantly promoted hair regrowth and increased the proliferation of hair growth factors in vitro and in vivo, suggesting potential as supplements for hair loss prevention.
March 2025 in “International Journal of Molecular Sciences” This study analyzed proteomic changes in Jiangnan cashmere goats' secondary hair follicles and found that the PLIN2 gene significantly impacts hair follicle growth cycles by affecting dermal papilla cell proliferation, offering insights into breeding strategies to enhance cashmere yield.
3 citations
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September 2024 in “International Journal of Molecular Sciences” This review examines how mathematical modeling of the MAPK pathway, enhanced by single-cell proteomic data, improves understanding of regulatory mechanisms, predicts system behavior, and guides experimental research, emphasizing recent developments in modeling and inference.
August 2025 in “Frontiers in Pharmacology” In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.
25 citations
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July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that applying topical imiquimod during mid and late telogen in mice activates hair follicle stem cells and influences immune cell infiltration, promoting hair cycle entry independently of Wnt signaling.