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Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Hair follicles prevent NK cell attacks to avoid hair loss.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Early treatment and regular check-ups are crucial for lupus patients to prevent progression and improve outcomes.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Frontal fibrosing alopecia might be linked to autoimmune diseases.

Sweat hypersensitivity can cause severe skin issues in horses.

The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

A woman with lupus and Kikuchi-Fujimoto disease improved with treatment.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

New treatments for severe hair loss often fail, but some patients see hair regrowth with specific therapies, and treatment should be tailored to the individual's situation.

Scalp biopsies help tell apart androgenetic alopecia and alopecia areata.

Diagnosing mycosis fungoides, a rare skin cancer, is difficult in elderly adults and requires careful examination to avoid mistaking it for less serious skin conditions.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

Severe digestive issues in DRESS need early endoscopy for better treatment.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.