research Alk1 Acts in Non-Endothelial VE-Cadherin+ Perineurial Cells to Maintain Nerve Branching During Hair Homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
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research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research A Transient Dermal Niche and Dual Epidermal Programs Underlie Sweat Gland Development
Sweat gland development involves two unique skin cell programs and a temporary skin environment.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin affects certain genes and pathways involved in cashmere goat hair growth.
research Dysregulation of Grainyhead-Like 3 Expression Causes Widespread Developmental Defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
research Updates in the Pathogenesis of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research The Potential Application of Ecklonia Cava Extract in Scalp Protection
Ecklonia cava extract may protect the scalp from pollution and improve its health.
research Gynecologic and Hormonal Comorbidities of Scarring Alopecia: A Retrospective Review
Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.
research Skin Morphogenesis by Coupling Biochemical-Bioelectric Signals: Calcium Oscillations Coordinate Dermal Cell Movement by Epidermis-Derived SHH Signaling During Feather Bud Orientation
Calcium signals and SHH guide the direction of feather growth in chicken skin.
research Dietary Grape Powder Inhibits Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
Eating grape powder may reduce the severity of skin allergy symptoms.
research 848 Genes Implicated in Lipid and Metabolic Regulation Downregulated in Central Centrifugal Cicatricial Alopecia
848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.
research Claudin-1 and Claudin-3 Maintain Proper Hair Follicle Structure and Regulate Telogen Effluvium
Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
research Advanced Age Impairs Self-Renewal and Biases Fate Choice of Hair Follicle Dermal Stem Cells
Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
research Aqueous Extract of Mentha Suaveolens Induces Nrf-2 Activation and Expression of Antioxidant and Detoxifying Enzymes in Human Keratinocyte HaCaT
Mint water extract boosts protective enzymes in skin cells.
research Nicotinic Acid Suppresses Sebaceous Lipid Synthesis of Human Sebocytes via Activating Hydroxycarboxylic Acid Receptor 2 (HCA2)
Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
research Orchestrated Cytotoxic and Skin Migratory Ability Lacking Self-Tolerance: Circulating γδT-Cells May Promote Alopecia Areata
The role of γδT-cells in causing alopecia areata remains unclear.
research Nrf2 Activation Enhances the Healing of Cutaneous Wounds Through the Activation of Hair Follicle Stem Cells
Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
research Efficacy of Topical Tofacitinib in Promoting Hair Growth in Non-Scarring Alopecia
Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.
research Both Lesional and Non-Lesional Skin from Acne Patients Shows Robust IL-17-Skewing and Upregulation of Antimicrobial Peptides
Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
research Cutaneous Lupus Erythematosus: Overview and Treatment
The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.
research Estrogen Induces VEGF Expression in Dermal Papilla Cells
Estrogen increases a growth factor in hair cells which might affect hair loss.
research Epidermal Wnt/Beta-Catenin Signaling Promotes Dermal Adipocyte Differentiation During Hair Follicle Morphogenesis and Regeneration
Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
research Identification of Key Genes and Signaling Pathways in Male Androgenetic Alopecia by Bioinformatics Analysis
Found key genes affecting hair loss, immune response, and skin development; more research needed for better treatments.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research Chronic Graft-Versus-Host Disease Exhibits Distinct Th1-Skewing and Barrier Abnormalities in the Skin
Chronic graft-versus-host disease in the skin shows strong Th1 immune response and unique barrier issues.
research The Effects of GPR40 Agonists on Hair Growth Are Mediated by ANGPTL4
GPR40 agonists help hair growth through the protein ANGPTL4.
research Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin
Hair follicles help attract immune cells to the skin during stress.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.