December 2025 in “The American Journal of Medical Sciences and Pharmaceutical Research” This study outlines how combined ultrasonic and infrared hair treatments may enhance hair restoration and performance by breaking down keratin disulfide bonds for better treatment access and sealing cuticle scales to preserve improvements, with potential applications in salon and home settings.
March 2025 in “ACS Applied Materials & Interfaces” This study found that using an ultrasound hollow microneedle array enhanced transdermal delivery of finasteride, accelerating hair regrowth in mice with androgenetic alopecia compared to other delivery methods.
February 2021 in “Reactions Weekly” Finasteride and dutasteride may cause macular abnormalities.
9 citations
,
November 2019 in “Cell calcium” This study found that a mutation causing Stormorken syndrome in mice led to skeletal abnormalities and unusual hair growth, showcasing the STIM1 R304W protein’s role in bone development and cell fate.
1 citations
,
January 2022 in “Journal of veterinary diagnostic investigation” This case report documented a novel presentation of a canine viral plaque appearing as a solitary exophytic keratin-filled mass, highlighting the need to differentiate it from a hair follicle tumor.
1 citations
,
January 2018 in “Acta dermato-venereologica” A teenager's hair with alternating white and dark bands, known as Pili annulati, is a genetic condition that is usually harmless and often considered attractive.
July 2025 in “Clinical Dermatology Review” In this case report, researchers observed multiple trichofolliculomas in family members, noting this as a rare manifestation of typically singular hair follicle hamartomas.
This case report describes an ulcerated lesion in the oral cavity of an 85-year-old man that has not responded to various treatments and remains without a conclusive diagnosis.
118 citations
,
December 2014 in “International Journal of Medical Sciences” This review discusses the potential of mesenchymal stem cells from the oral cavity for tissue regeneration in oral and maxillofacial surgery but reports no new clinical results.
48 citations
,
March 2019 in “Frontiers in Physiology” This review discusses the typical wound healing process in skin and the oral cavity, and emphasizes the research focus on achieving scarless healing in adult skin, but reports no new clinical results.
2 citations
,
November 2020 in “International Journal of Otorhinolaryngology and Head and Neck Surgery” The researchers reported that nasolabial flaps were effective for reconstructing small to intermediate oral cavity defects in early oral cancer patients, with overall good cosmetic and functional outcomes despite some complications.
October 2022 in “Indian journal of anatomy and surgery of head, neck and brain” This study concluded that the inferiorly based nasolabial flap is an effective and reliable option for reconstructing oral cavity defects in patients with oral submucous fibrosis, achieving significant improvements in mouth opening without serious complications.
July 2025 in “Bulgarian Portal for Open Science” In this study, researchers explained that healing of extensive skin defects involves granulation filling the wound cavity, followed by epithelialization from skin edges and hair follicles, which are crucial steps in wound healing.
95 citations
,
September 2012 in “Oman Medical Journal” This review discusses the structure, types, and distribution of keratins and their role in tissue fragility disorders, particularly within the oral cavity, without presenting new clinical findings.
18 citations
,
April 2016 in “American Journal of Dermatopathology” This case series highlights that nail clipping can aid in early detection and surgical planning of onychomatrical tumors by distinguishing between benign and potentially malignant growths based on the cavities' average dimensions.
13 citations
,
January 2012 in “International journal of trichology” This case study describes a 14-year-old girl with pili annulati who had fragile hair, which may be due to cavities within the hair shafts as seen in electron microscopic examinations.
6 citations
,
May 2020 in “JAMA Ophthalmology” This study suggests that the use of 5α-reductase inhibitors in men may be associated with macular abnormalities, characterized by cystoid changes and foveal cavitation, potentially progressing to more severe defects.
1 citations
,
May 2025 in “The Journal of Rheumatology” In this case report, researchers described a 48-year-old man with systemic lupus erythematosus who developed a fungus ball (aspergilloma) within a tuberculosis cavity, a complication rarely reported in such patients, emphasizing the role of CT scans in diagnosis and the potential need for surgical intervention.
91 citations
,
July 2020 in “JAMA Dermatology” This study suggests that minoxidil may improve hypotrichosis in patients with ARWH due to LIPH variants, but a possible genetic factor could affect its efficacy within families.
13 citations
,
January 2009 in “The Open Dermatology Journal” This article describes a case of oral pigmentation that posed a diagnostic challenge in determining Addison’s disease and includes a brief review, reporting no new clinical results.
3 citations
,
October 2020 in “Dermatology Practical & Conceptual” This abstract reviews the bubble hair abnormality caused by high-temperature styling tools and reports no new experimental results.
May 2026 in “Drug Delivery” This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.
This study found that Tianqi trichogen promoted hair growth in tested animals, with no observed photoallergic reactions or significant skin allergies.
94 citations
,
December 2018 in “Dentistry Journal” This review article explores the potential of various mesenchymal stem cell populations derived from oral tissues, such as DPSCs and hPCy-MSCs, in bone tissue engineering and regeneration, detailing their high plasticity and clinical applications in dental procedures.
85 citations
,
August 2021 in “Materials & Design” This review summarizes advancements in biomaterial-based encapsulation of probiotics for diverse biomedical uses and reports no new clinical results, while outlining current challenges and future research directions.
8 citations
,
April 2014 in “Clinical and Experimental Dermatology” This study suggests that eruptive vellus hair cysts often have atypical pathological changes and likely originate from the infrainfundibulum and sebaceous duct based on keratin expression analysis.
5 citations
,
January 2009 in “International Journal of Trichology” This case report documents a rare association between atopic eczema and pili annulati in two siblings from north India, an unusual finding not previously reported in the literature.
4 citations
,
July 2020 in “Research Square (Research Square)” This study provided the crystal structure of the human steroid 5α-reductase 2 enzyme and identified key molecular mechanisms for testosterone reduction and finasteride inhibition, aiding in understanding disease-causing mutations and potentially facilitating new drug development.
4 citations
,
August 2008 in “Plastic & Reconstructive Surgery” This study reports that the composite galeal frontalis pericranial flap can be successfully used for reconstruction in anterior cranial base surgery, effectively sealing cerebrospinal fluid leaks, while minimizing complications like numbness and skin necrosis.
2 citations
,
April 2021 in “Journal of Mind and Medical Sciences” This study reports a case of chylous peritonitis due to acute pancreatitis diagnosed intraoperatively in a 23-year-old man presenting with abdominal pain and milky-like fluid effusion.