Enanthem in Patients With COVID-19 and Skin Rash
July 2020
in “
JAMA Dermatology
”
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This case series described the appearance of enanthem (oral cavity lesions) in 21 patients with COVID-19 and skin rash, confirmed by real-time reverse transcriptase–polymerase chain reaction. Enanthem was observed in 6 patients (29%), with lesions classified as macular, petechial, or macular with petechiae, all located in the palate. The study found that enanthem, particularly with a petechial pattern, strongly suggested a viral etiology rather than a drug reaction. The latency between COVID-19 symptoms and mucocutaneous lesions averaged 12.3 days. The study was limited by the small sample size and lack of a control group.