Enanthem in Patients With COVID-19 and Skin Rash

July 2020 in “ JAMA Dermatology ”

Juan Jimenez‐Cauhe, Daniel Ortega‐Quijano, Dario de Perosanz‐Lobo, Patrícia Burgos‐Blasco, Sergio Vañó‐Galván, Montse Fernández‐Guarino, Diego Fernández‐Nieto

minoxidil autosomal recessive woolly hair ARWH LIPH pathogenic variants hypotrichosis hair shaft diameters dry scalp skin trichiasis hypertrichosis Rogaine

TLDR Minoxidil can improve hair growth in some patients with woolly hair due to LIPH variants, with varying responses and mild side effects.

This case series described the appearance of enanthem (oral cavity lesions) in 21 patients with COVID-19 and skin rash, confirmed by real-time reverse transcriptase–polymerase chain reaction. Enanthem was observed in 6 patients (29%), with lesions classified as macular, petechial, or macular with petechiae, all located in the palate. The study found that enanthem, particularly with a petechial pattern, strongly suggested a viral etiology rather than a drug reaction. The latency between COVID-19 symptoms and mucocutaneous lesions averaged 12.3 days. The study was limited by the small sample size and lack of a control group.

View this study on doi.org →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

5 citations, July 2020 in “JAMA Dermatology”

Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.

research Faculty Opinions Recommendation of Association of Topical Minoxidil with Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

July 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Genetic Hair Disorders: A Review

26 citations, July 2019 in “Dermatology and Therapy”

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

research Development of Woolly Hair and Hairlessness in a CRISPR-Engineered Mutant Mouse Model with KRT71 Mutations

July 2023 in “Cells”

Researchers made a mouse model with curly hair and hair loss by editing a gene.

research Highly Prevalent LIPH Founder Mutations Causing Autosomal Recessive Woolly Hair/Hypotrichosis in Japan and the Genotype/Phenotype Correlations

15 citations, February 2014 in “PloS one”

LIPH mutations in Japan cause varying degrees of hair loss and woolly hair.

Enanthem in Patients With COVID-19 and Skin Rash

Related Community Posts Join

community Pirfenidone - The answer to fibrosis and baldness

community Why balding gets worse in every generation?

community Study shows significant improvement in hair with topical minoxidil and oral Vitamin d compared to just topical minoxidil alone.

community Studies on Minoxidil show an increase in hair count shortly after starting treatment

community Why is Minoxidil not enough for hair loss? (No fin)