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Melatonin improved mental health and metabolism in women with PCOS.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.

Ficus carica extract improved fertility in rats and may help with certain health conditions.

COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.

Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Royal jelly can protect the heart from damage caused by paclitaxel.

Minoxidil causes excessive hair growth, but depilatory agent removes it safely and effectively.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Too much topical minoxidil can cause excessive hair growth, but stopping treatment reverses it.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.

Grape seed extract may safely and effectively help prevent lung cancer.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Some psychiatric drugs can cause severe hair loss, especially valproic acid, and it's more likely in women or those with thyroid issues or past hair loss.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.