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The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Using natural polyphenol cross-linkers like tannic acid and green tea extract in perm treatments improves curling and protects hair.

Noggin is necessary to start the hair growth phase in skin after birth.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Estrogen receptors may not affect mouse hair growth as previously thought, and oxybenzone in sunscreen is stable in sunlight.

Hair loss is significantly linked to lower levels of certain genes in hair follicles.

The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Tradescantia plants can effectively test for the toxicity of harmful algae.

Genetic marker rs12558842 strongly linked to male hair loss.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

The document concludes that cosmetics need biocompatible, eco-friendly ingredients due to aging populations and demand for effective products.

Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.

The compound was successfully made and shows potential for treating prostate cancer.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The new skin patch with human matrix and antibiotic improves wound healing.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.