24 citations
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August 2009 in “Expert opinion on pharmacotherapy” This article highlights the benefits of combining calcipotriene and betamethasone for treating localized plaque-type, scalp, and nail psoriasis, enhancing effectiveness while reducing side effects compared to single-agent therapies.
15 citations
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December 2009 in “PubMed” This case study highlights a pediatric instance of eruptive vellus hair cysts partially responding to calcipotriene cream, aiming to remind clinicians about this often overlooked condition.
6 citations
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March 2019 in “JAAD case reports” This review discusses treatment strategies for alopecia areata, emphasizing current immunomodulation approaches but reports no new clinical results.
1 citations
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April 2009 in “Expert Review of Dermatology” This study found that the once-daily gel combining calcipotriene and betamethasone dipropionate was more effective and faster in treating scalp psoriasis compared to individual treatments, with a similar safety profile.
May 2025 in “JEADV Clinical Practice” This study found that using calcipotriene and betamethasone dipropionate cream in a real-world setting significantly improved clinical outcomes and patient quality of life for adults with mild-to-moderate scalp psoriasis, especially among those with higher adherence, demonstrating high treatment satisfaction.
This case study presented by the researchers describes the effective use of topical calcipotriene ointment in treating a 6-year-old girl with en coup de sabre scleroderma, resulting in normalization of the sclerotic skin, hair regrowth, and improved pigmentation.
May 2020 in “JAAD case reports” This source describes a previous case report that combined anthralin and calcipotriene to treat alopecia areata, showing promising results, but highlights that further research is needed to understand the mechanisms and potential benefits of this combination therapy.
20 citations
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January 2000 in “Dermatologic Clinics” This article discusses recent advancements in treatments for psoriasis, including new drug approvals and innovative therapeutic approaches, but reports no new clinical results.
1 citations
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October 2024 in “The American Journal of Gastroenterology” In this case report, a patient with Crohn's disease experienced alopecia and psoriasiform reactions attributed to anti-TNF therapy, which improved after switching to Ustekinumab.
January 2022 in “Clinical Cases in Dermatology” This review discusses treatment strategies for scalp psoriasis, highlighting the use of topical agents and challenges in managing this difficult form of psoriasis, but provides no new clinical results.
March 2019 in “Reactions Weekly”
10 citations
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April 2020 in “Dermatology and therapy” In this study of 35 patients with scalp alopecia areata, calcipotriol ointment led to faster and greater hair regrowth than clobetasol, though differences were not statistically significant.
5 citations
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January 1995 in “Journal of Dermatological Treatment” This study suggests that topical calcipotriol did not significantly enhance hair growth when combined with SADBE in patients with severe alopecia areata.
16 citations
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May 2006 in “The Journal of Dermatology” This study reported successful treatment of peeling skin syndrome using topical calcipotriol.
1 citations
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December 2022 in “Journal of cosmetic dermatology” This study found that combining a potent steroid with a vitamin D analogue may offer more convenient treatment for localized alopecia areata than using a superpotent steroid alone, with comparable efficacy but fewer side effects.
July 1996 in “Clinical and Experimental Dermatology” This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.
38 citations
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June 2015 in “PubMed” This study found that topical calcipotriol may safely and effectively treat mild-to-moderate patchy alopecia areata, with significant hair regrowth observed in the majority of participants over 12 weeks.
16 citations
,
January 2000 in “Journal of dermatological treatment” This study found that calcipotriol scalp solution was more effective than a coal tar-based shampoo for treating mild to moderate scalp psoriasis and showed continued efficacy with long-term use.
39 citations
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January 2017 in “Dermatologic Therapy” This study found that topical calcipotriol lotion resulted in hair regrowth in 59.1% of alopecia areata patients, with better response observed in those with lower serum vitamin D levels.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” This study investigated the efficacy and safety of a gel combining topical calcipotriol and steroid for alopecia areata. It found the combination worked similarly to steroids alone in reducing hair loss, but with fewer side effects.
August 2018 in “Journal of the American Academy of Dermatology” Calcipotriol may effectively treat hair loss in alopecia areata, working better in children than adults.
9 citations
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September 2019 in “Clinical Cosmetic and Investigational Dermatology” In this article, the authors reported that calcipotriol/betamethasone dipropionate aerosol foam significantly improved scalp psoriasis symptoms in three patients by reducing itching and improving flaky patches within a four-week treatment period, confirming its efficacy and enhanced skin penetration compared to older formulations.
1 citations
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January 2021 in “Journal of clinical and diagnostic research” In this study, adding topical calcipotriol 0.005% to topical clobetasol 0.05% significantly improved treatment efficacy for Alopecia Areata compared to using clobetasol alone, as evidenced by a greater reduction in SALT scores over 24 weeks.
3 citations
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March 2019 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” In this study, topical calcipotriol was found to be more effective than oral vitamin D for improving mild to moderate alopecia areata, with a 68% improvement rate and no correlation between serum vitamin D levels and treatment efficacy.
January 2026 in “Annals of Dermatology” In this study, 80% of pediatric patients with alopecia areata treated with calcipotriol/betamethasone ointment showed hair regrowth over 12 weeks, suggesting it may be an effective option, though 20% had no improvement or worsening symptoms.
1 citations
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May 2024 in “Journal of Pakistan Association of Dermatologists” This study found that topical calcipotriol was significantly more effective than topical tacrolimus in promoting hair growth for alopecia areata patients, demonstrating 67% efficacy compared to 33% efficacy with tacrolimus over a 6-month period.
May 2024 in “Journal of Pakistan Association of Dermatologists” In this randomized control trial, researchers reported that topical calcipotriol was more effective than topical tacrolimus in promoting hair growth for patients with alopecia areata over a 6-month period, with a statistically significant difference in efficacy.
9 citations
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January 2019 in “International Journal of Trichology” In this study, combining topical calcipotriol with mometasone results in greater improvement in alopecia areata treatment compared to using mometasone alone, as evidenced by a more significant reduction in SALT score over 24 weeks.
3 citations
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January 1996 in “Journal of Dermatological Treatment” In this study, twice daily application of 3 μg/g calcitriol ointment was reported to be safe, effective, and well tolerated for treating moderate to severe chronic plaque psoriasis on the face and surrounding areas.
18 citations
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July 2018 in “Journal of Cosmetic Dermatology” This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.