Calcipotriene/Betamethasone in the Treatment of Psoriasis: A Review Article
August 2009
in “
Expert opinion on pharmacotherapy
”
TLDR The combination of calcipotriene and betamethasone is more effective and has fewer side effects for treating psoriasis.
Plaque-type psoriasis, affecting approximately 1-3% of the Caucasian population, was commonly treated with topical corticosteroids and vitamin D3 analogues. The combination of calcipotriene and betamethasone dipropionate optimized treatment by merging the keratinocyte differentiation and antiproliferative effects of vitamin D3 analogues with the anti-inflammatory properties of steroids. This combination enhanced effectiveness and reduced side effects compared to using a single topical agent. The review highlighted the benefits of this combination therapy for localized plaque-type, scalp, and nail psoriasis.
