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Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

Balanced vitamin D levels are crucial to delay aging and prevent related diseases.

Wearing headcovers doesn't affect male-pattern hair loss severity.

Improving mitochondrial health may better treat atherosclerosis than antioxidants.

Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.

Women may need different blood pressure guidelines than men for heart disease prevention.

Modified PRP therapy successfully treated severe alopecia unresponsive to traditional methods.

PAD is common but often missed, needing lifestyle changes and medication for better outcomes.

Retinoids are effective for severe acne and psoriasis but can cause serious side effects and birth defects.

The Rotterdam Study aims to understand various diseases in older adults.

Finasteride helps female-pattern hair loss.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

Dermatological conditions are complex and treatments often have mixed results.

A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.

Oxygen levels can drop during liver transplant if bypass pressures are too high, but other reasons should be checked first.

Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.

The diphosphonate was the most effective at preventing calcification in rats.

The document reports a rare case of ECCL with a new association with optic disc colobomas.

Insulin resistance plays a key role in PCOS, and lifestyle changes, weight loss, and medications like metformin can help manage it.

Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.

Porphyria cutanea tarda causes skin issues due to an enzyme deficiency.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

The document concludes that proper diagnosis and treatment of hair shaft disorders require understanding their unique causes and avoiding hair-damaging practices.

Early detection and multidisciplinary treatment are crucial for managing Papillon-Lefévre syndrome.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.