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SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Hair keratin-associated proteins are essential for strong hair, with over 80 genes showing specific patterns and variations among people.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

FFA's causes may include environmental triggers and genetic factors.

Msx2 and Foxn1 are both crucial for hair growth and health.

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

AR polyglycine repeat doesn't cause baldness.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.