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This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This case report suggests that intradermal botulinum toxin type A may alleviate pruritus and reduce papules in Fox-Fordyce disease, improving quality of life without serious adverse effects for at least six months.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.

This study found that adherence to topical hydrocortisone in adults with atopic dermatitis was inconsistent and not significantly different across different medication vehicles, though disease severity improved markedly within 2 weeks.

The adapalene-benzoyl peroxide gel works better and faster for acne treatment than using either ingredient alone, with manageable side effects.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

This study observed that using ex vivo gene therapy to modify skin cells in a pre-graft model improved dermal-epidermal junction adhesion strength and maintained collagen production over time, suggesting a potential treatment approach for recessive dystrophic epidermolysis bullosa skin wounds.

In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.

This article reviews the promising ease of drug administration via transdermal and other topical routes, highlighting their potential for high patient compliance and reduced side effects but provides no new clinical results.

This study found that combining a GnRH agonist with a low-dose oral contraceptive was more effective in treating hirsutism than either agent alone and prevented hypoestrogenic side effects.

This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.

Dissolvable microneedles are a promising, painless method for effective skin treatments.

This abstract details known indications, categories, and potential reactions for various drugs, including anorexiants, estrogens, NSAID analgesics, cardiac glycosides, and migraine preventives, without reporting new clinical results.

In this study, Juvéderm repeat treatments maintained wrinkle correction in nasolabial folds for up to 21 months and required significantly less filler than the initial treatment, indicating potential benefits for patients.

This study concluded that bimatoprost 0.03%, applied either twice or once daily, is safe, well-tolerated, and effective in improving eyebrow fullness and darkness in individuals with eyebrow hypotrichosis.

This literature review of hormonal implants in Brazil highlights their expanding usage beyond contraceptive and hormone replacement purposes, noting aesthetic desires like muscle mass gain. However, significant side effects such as cardiovascular events and psychological complications are frequently reported, potentially outweighing the benefits.

This study reports cases of arterial embolization occurring due to the injection of hyaluronic acid (Restylane®).

This study developed a consensus document to guide danazol discontinuation in hereditary angioedema patients, enhancing the standardization and safety of treatment protocols.

This study concluded that combining cyanoacrylate skin surface stripping with particle-based antigen delivery effectively targets HIV-1 p24 protein to skin cells, supporting its potential for needle-free transcutaneous vaccination.

This study suggests that PrEP implants for HIV prevention are potentially acceptable among gay and bisexual men, with positive attitudes toward implant features and minor insertion-related effects.

This study found that intracutaneous injections of nandrolone phenylpropionate specifically induced local epidermal thickening and increased sebaceous gland volume in female hairless hamsters, independent of a dermal inflammatory response.

This study found that in mouse models, the novel NF-κB inhibitor DHMEQ improved symptoms of atopic dermatitis as effectively as tacrolimus or betamethasone.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

This study of Black and Hispanic inner-city teens found that Norplant retention rates were 71% at one year and 62% at two years, with a history of induced abortion predicting higher continuation.

This study found that a topical gel formulation containing Dutasteride-loaded niosomes was stable for 90 days and facilitated improved drug release, suggesting potential for enhanced bioavailability in topical applications.

This paper describes a new scalable synthesis method for Dutasteride, highlighting its potential for large-scale commercial production.

This case report describes a 54-year-old woman with familial dyskeratotic comedones who experienced slight improvement in her skin lesions after three months of treatment with topical retinoids and urea cream.