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research Breaking the biofilm- A persistent case of deep pyoderma in a Bullykutta dog
In this case report, a persistent skin infection in a Bullykutta dog was resolved with a 10-day treatment regimen of Sulphamethoxazole, trimethoprim, omega fatty acids, and topical therapy after previous treatments failed.
research Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model
In this animal study, researchers found that finasteride reduced bacterial infection and inflammation in chronic bacterial prostatitis, with the greatest effect when combined with ciprofloxacin.
research Supplements That May Counteract Side Effects from Conventional Cancer Therapies
This review discusses supplements used to alleviate side effects of chemotherapy, highlighting various natural remedies, but reports no original clinical research findings.
research [Finasteride--ris of "unintentional doping"].
research Randomisierte, doppelblind Placebo-kontrollierte Studie zur Wirksamkeit eines spezifischen, CYP (Cystin, Medizinalhefe, Pantothensäure)-Komplex-haltigen Arzneimittels zur Nahrungsergänzung (Pantogar) bei Frauen 60+ mit Haarausfall
This study found no significant difference in anagen rate improvement between the CYP-based dietary supplement and placebo in women over 60 with telogen effluvium, possibly due to variable patient inclusion related to hair growth seasonality.
research Bicalutamide: A potential new oral anti-androgenic drug for female pattern hair loss - A case series
This case series evaluated the use of oral bicalutamide with low-dose oral minoxidil in women with female pattern hair loss who didn't respond to minoxidil alone, finding that 96.6% showed improvement after six months without adverse effects.
research Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia
This study found that cubosomes combined with dissolving microneedles enhanced transdermal penetration and hair growth efficacy of beta-sitosterol for treating alopecia.
research Cabergoline therapy against hyperadrenocorticism in a dog
In this case report, a 9-year-old Labrador with hyperadrenocorticism showed improvement in clinical signs after three months of treatment with cabergoline, suggesting it may be an effective alternative treatment for this condition in dogs.
research Open-label placebos reduce hair cortisol concentrations and psychological distress - a randomized controlled trial
In this study, university students given open-label placebo treatment reported reduced psychological distress and lower hair cortisol concentrations during stressful exams, suggesting that these placebos may help manage the physiological and psychological impacts of prolonged stress.
research TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice
This study found that etifoxine pretreatment reduced neuroinflammation and improved cognitive function in LPS-induced neuroinflammation in mice, potentially through increased neurosteroid synthesis and reduced apoptosis.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research PD05-05 SINGLE CENTRE EXPERIENCE OF CHELATING AGENTS IN CYSTINURIA
This study observed that discontinuation rates due to side effects were similar for penicillamine and tiopronin among cystinuria patients, and switching to the alternative agent was beneficial for half of those experiencing issues.
research Bioidentical Hormone Replacement Therapy at a Hormone Clinic Causing Significant Virilization in a Post-Menopausal Women
This case report highlights the adverse effects of unmonitored bioidentical hormone replacement therapy, emphasizing the need for patient education about its safety and efficacy compared to FDA-regulated hormones.
research Doxil (Caelyx): an exploratory study with pharmacokinetics in patients with hormone-refractory prostate cancer
In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.
research Editorial Comment
This study observed that the out-of-pocket prices for generic medications used to treat benign prostatic hyperplasia can vary by up to 500% among pharmacies in the Pittsburgh area, with chain pharmacies pricing significantly higher than independents.
research Preparation of novel polymeric microspheres for controlled release of finasteride
The study concluded that poly(propylene carbonate maleate) microspheres effectively encapsulated finasteride, achieving a biphasic release with prolonged drug release over 5-6 weeks in vitro.
research Poster abstract: Novel dissolving microarray patches for intradermal delivery of finasteride
This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.
research A Randomized Placebo-Controlled Multicentre Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)
This study evaluates finasteride's safety and efficacy for treating male chronic pelvic pain syndrome, but the abstract does not report any results.
research α1A-blockers's combined with prozac for the treatment of premature ejaculation
This study found that combining α 1A-blockers with Prozac was more effective for treating premature ejaculation than using Prozac alone.
research Decision letter for "The Comparative Effects Between Long‐Term and Short‐Term Treatment of Finasteride on Anxiety‐Like and Depression‐Like Behaviors in Early Senescent Male Rats"
research Decision letter for "The Comparative Effects Between Long‐Term and Short‐Term Treatment of Finasteride on Anxiety‐Like and Depression‐Like Behaviors in Early Senescent Male Rats"
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
In this randomized study, BAY 1158061, a prolactin receptor antibody, was found to be safe, well-tolerated, and exhibited low immunogenicity in healthy postmenopausal women, but had no effect on serum prolactin levels compared to placebo.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research Self-Emulsifying Drug Delivery Systems (SEDDS): Measuring Energy Dynamics to Determine Thermodynamic and Kinetic Stability
This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
research Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model
This study found that Croton membranaceus root extract induced CYP1A2 and GSTM1 enzymes but inhibited CYP3A4 and CYP2D6 in rat livers, suggesting caution in its use with other drugs.
research Tackling Adverse Effects
research Oral administration of berberine represses macrophage activation-associated benign prostatic hyperplasia: a pivotal involvement of the NF-κB
This animal study found that berberine may alleviate benign prostatic hyperplasia by reducing inflammation and oxidative stress through inhibition of the NF-κB signaling pathway.
research Study on Human Bioequivalency of Two Preparations of Finasteride
This study found that the pharmacokinetic profile of finasteride capsules and tablets in healthy volunteers is bioequivalent.
research Two Transgender Men Receiving Subdermal Testosterone Pellets for Gender Affirmation
This case report describes two transgender men using subdermal testosterone pellets for gender affirmation, finding they tolerated the treatment, but one returned to injections; firm conclusions on pellets' suitability require further study.