January 2015 in “International Journal of Nanomedicine” In this animal study, the researchers found that administering anionic lipid nanoemulsions called squarticles increased survival rates and mitigated the adverse effects of amitriptyline overdose in rats.
86 citations
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July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
July 2025 in “Future Journal of Pharmaceuticals and Health Sciences” This study developed a polyherbal chocolate formulation aimed at managing PCOS and hormonal balance, finding that formulation F2 showed excellent organoleptic properties and stability, with future in vivo studies being suggested.
35 citations
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October 2005 in “European journal of pharmaceutics and biopharmaceutics” This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.
April 2016 in “Journal of Investigative Dermatology” This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.
This article reviews the contraceptive agent Depo-Provera, discussing its effectiveness, potential side effects, and safety concerns, but reports no new clinical results.
March 2025 in “Carbohydrate Polymer Technologies and Applications” In this study, researchers developed a carboxylated β-cyclodextrin formulation to enhance finasteride's physicochemical properties, achieving an encapsulation efficiency of about 85% and indicating potential for controlled drug release in therapeutic applications. Their findings suggest this inclusion complex could improve delivery of hydrophobic drugs like finasteride.
January 2008 in “xPharm: The Comprehensive Pharmacology Reference” 6 citations
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November 2015 in “JAMA” This study found that oral contraceptive pills improve mild hirsutism, while flutamide and spironolactone are beneficial for more severe cases, but other therapies show inconsistent or no benefit.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes Protetox as a natural dietary supplement that aids in weight loss by detoxifying the body, utilizing a blend of plant-based ingredients and antioxidants, and claims users have reported significant weight loss without changing their diet or exercise routines.
April 2018 in “The Journal of Urology” This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
8 citations
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March 2023 in “Polymers” This study suggests that a chitosan-coated omeprazole-loaded nanoemulgel formulation may effectively treat certain skin infections due to its demonstrated antimicrobial properties and enhanced antibacterial activity.
October 2025 in “Animals” This study reported that horses with pituitary pars intermedia dysfunction had improved coat condition, advanced shedding, and better quality of life when treated with blue light masks.
March 2026 in “Food Science & Nutrition” In this study, high-dose Arachis hypogaea root extract significantly reduced prostate weight and markers of glandular hyperplasia in testosterone-induced BPH in mice, with associated changes in inflammatory gene expression and beneficial shifts in gut microbiota.
6 citations
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June 1994 in “Journal of Animal Science” This study found that none of the depigmenting compounds tested in beef heifers produced a permanent depigmenting effect, though visible depigmentation lasted up to 3 months.
This article suggests using oral contraceptives with antiandrogenic properties for women with virilization symptoms like acne and advises higher doses of antiandrogens for severe acne, androgenic alopecia, or idiopathic hirsutism.
5 citations
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June 2012 in “QJM: An International Journal of Medicine” This article reviews the historical development of pharmacology up to the mid-20th century and outlines its transition from a support role in therapeutics to a distinct scientific discipline, but reports no new findings.
15 citations
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November 1994 in “International Journal of Dermatology” This study found that while the combination of oral propranolol and intradermal injections in guinea pigs led to psoriasiform changes, it did not fully mimic psoriasis.
8 citations
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October 1996 in “JAMA” This case report discusses a 17-year-old student's contraceptive use and pregnancy history without providing new research findings.
This report discusses the FDA's rejection of Aveed, a long-acting testosterone injection, due to safety concerns despite divided advisory committee opinions, without presenting new clinical data.
5 citations
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September 2011 in “Bioorganic & Medicinal Chemistry Letters” This study identified pantolactam based compounds as effective topical antagonists of the androgen receptor, reducing sebum components in a hamster model.
20 citations
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June 1985 in “Toxicologic Pathology” In this study, prolonged high-dose steroid treatment in rats caused several pathological changes, some of which regressed, particularly improvements in mammary gland tumors and pituitary-related symptoms, after stopping treatment.
This meta-analysis found that combination oral contraceptive pills effectively treat hirsutism but recommends adding an antiandrogen if response is inadequate after six months.
1 citations
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August 2021 in “Preventive Medicine” This study found that non-adherence to medication in the Prostate Cancer Prevention Trial was associated with increased all-cause mortality unrelated to prostate cancer.
11 citations
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August 2014 in “Current Urology Reports” This review discusses the known effects of medications for benign prostatic hyperplasia on sexual function and mechanisms of dysfunction but reports no new clinical results.
October 2025 in “Carbohydrate Polymer Technologies and Applications” This study investigated improving Finasteride's water solubility using trimethyl-β-cyclodextrin (TM-β-CD) and β-cyclodextrin (β-CD) as carriers, finding that β-CD improved Fin's cumulative release, while TM-β-CD enhanced its solubility, with computational data supporting these outcomes.
4 citations
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March 2010 in “International Journal of Oral Science” This study concluded that the Chinese herbal medicine Xianhuayin effectively reversed DMBA-induced premalignant lesions in the buccal pouch of golden hamsters.
1 citations
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December 2011 in “Arzneimittelforschung” This study found that the compound 9,11-dehydrocortexolone 17alpha-butyrate (CB-03-04) showed strong local antiandrogenic activity in animal models, suggesting potential for treating prostate conditions.
January 2026 in “Buletin Veteriner Udayana” In this study, a female dog with ectoparasite infestation was treated for two weeks using wormectin, diphenhydramine, chlorpheniramine maleate, dexamethasone, and amoxicillin, resulting in improved symptoms such as reduced itching, closure of skin ulcers, and hair regrowth.