research Stem Cells and Alopecia: A Review of Pathogenesis
Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
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research Targeted Elimination of Follicular Label-Retaining Cells by Photo-Induced Cell Killing Caused a Defect in Follicular Renewal in Mice
Killing specific cells in hair follicles can lead to hair growth problems in mice.
research Life of the B10 Mouse: A View from the Hair Follicles and Tissue Stem Cells
Mice skin matures by day 200, leading to aging signs like curved hair follicles and white hairs due to changes in skin stem cells.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research Extracellular Proteoglycan Decorin Maintains Human Hair Follicle Stem Cells
Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
research The Human Papillomavirus Type 11 Upstream Regulatory Region Triggers Hair-Follicle-Specific Gene Expression in Transgenic Mice
The HPV type 11 region activates hair-specific gene expression in mice.
research Life of the B10 Mouse: A View from the Hair Follicles and Tissue Stem Cells
Mouse skin and hair aging starts at 200 days, with changes in hair follicles and more white hairs as signs of aging.
research Association of Fibrosis in the Bulge Portion with Hair Follicle Miniaturization in Androgenetic Alopecia
Fibrosis in the bulge area of hair follicles can cause hair thinning in male pattern baldness, and drugs that inhibit fibrosis might help reverse this.
research CD34 Defines Melanocyte Stem Cell Subpopulations With Distinct Regenerative Properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
research Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing
Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
research Controlling the Stem Cell Niche: Right Time, Right Place, Right Strength
Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
research Advances in Hair Diseases
The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
research The Thinning Top: Why Older People Have Less Hair
Old people have less hair because their hair follicles don't regenerate as well, not because of fewer stem cells, and a protein called follistatin might help reactivate hair growth.
research Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus
The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.
research Unexpected Expression of Hemoglobin Alpha as an Endogenous Antioxidant in Epidermal Keratinocytes
Hemoglobin α acts as an antioxidant in skin cells, especially protecting hair follicle stem cells from UV damage.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Hair Matters in Melanoma Biology
The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
research Investigating the Use of Autologous Stem Cell Therapy in the Treatment of Androgenetic Alopecia
Autologous stem cell therapy may effectively increase hair density in Androgenetic Alopecia.
research Inherited Disorders of the Hair
The study concluded that genetic mutations affect human hair diseases and identified key genes and pathways involved in hair growth and cycling.
research Proceedings From the Third Intercontinental Meeting of Hair Research Societies
The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
research Conditional Ablation of JAK-STAT5 Signaling Induces Anagen Hair Growth
Blocking JAK-STAT5 signaling in mice leads to hair growth.
research Epidermal Stem Cells Do Not Communicate Through Gap Junctions
Epidermal stem cells don't use gap junctions to communicate.
research Effects of Gamma Rays on the Regeneration of Murine Hair Follicles in the Natural Hair Cycle
Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
research The Effects of Gamma Rays on the Regeneration of Hair Follicles Are Carried Over to Later Hair Cycles
Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
research Hair Biology and Androgenetic Alopecia
Hair loss caused by genetics and hormones; more research needed for treatments.
research Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles
Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
research Telocytes in Human Skin – Are They Involved in Skin Regeneration?
Telocytes might help with skin repair and regeneration.
research The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
research Human Platelet Lysate Versus Minoxidil Stimulates Hair Growth by Activating Anagen Promoting Signaling Pathways
Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.