Proceedings From the Third Intercontinental Meeting of Hair Research Societies

    May 2003 in “ Journal of Investigative Dermatology ”
    Paul R. Bergstresser, David Whiting
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    TLDR The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
    The document from the Third Intercontinental Meeting of Hair Research Societies, dated June 1, 2003, covers a range of topics in hair research. It discusses the importance of steroid hormones, particularly testosterone and dihydrotestosterone, in hair physiology and the effectiveness of finasteride in treating male-pattern alopecia. The biology of hair follicle stem cells, including their multipotency and localization in the bulge region, is explored, with Connexin 43 identified as a negative marker for keratinocyte stem cells. The document also examines animal and in vitro models for studying hair follicle interactions, alopecia areata as a model for autoimmune skin diseases, and preliminary classification for scarring alopecias. Androgenetic alopecia in women is associated with higher levels of 5% reductase and androgen receptors, with topical minoxidil being the only treatment mentioned. The TrichoScan method is introduced for hair loss monitoring, a study on Japanese women provides parameters for grading female diffuse alopecia, and new insights into keratin-associated protein genes and the development of the hair follicle pigmentary unit are presented.
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      in Research/Science  9 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

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      in Research/Science  141 upvotes 5 months ago
      Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 1 year ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.
      Can I still save my hairline at age of 15?

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      in General  471 upvotes 2 weeks ago
      A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

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