Proceedings From the Third Intercontinental Meeting of Hair Research Societies
June 2003
in “
Journal of Investigative Dermatology
”
steroid hormones testosterone dihydrotestosterone finasteride male-pattern alopecia hair follicle stem cells multipotency bulge region Connexin 43 keratinocyte stem cells alopecia areata autoimmune skin diseases scarring alopecias androgenetic alopecia 5% reductase androgen receptors topical minoxidil TrichoScan female diffuse alopecia keratin-associated protein genes hair follicle pigmentary unit DHT Propecia androgenic alopecia Rogaine PRP
TLDR The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
The document from the Third Intercontinental Meeting of Hair Research Societies, dated June 1, 2003, covers a range of topics in hair research. It discusses the importance of steroid hormones, particularly testosterone and dihydrotestosterone, in hair physiology and the effectiveness of finasteride in treating male-pattern alopecia. The biology of hair follicle stem cells, including their multipotency and localization in the bulge region, is explored, with Connexin 43 identified as a negative marker for keratinocyte stem cells. The document also examines animal and in vitro models for studying hair follicle interactions, alopecia areata as a model for autoimmune skin diseases, and preliminary classification for scarring alopecias. Androgenetic alopecia in women is associated with higher levels of 5% reductase and androgen receptors, with topical minoxidil being the only treatment mentioned. The TrichoScan method is introduced for hair loss monitoring, a study on Japanese women provides parameters for grading female diffuse alopecia, and new insights into keratin-associated protein genes and the development of the hair follicle pigmentary unit are presented.
