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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.