18 citations
,
October 2016 in “Clinics in Dermatology” This review discusses the challenges and complexities in diagnosing and managing acne and reports no new clinical findings; it emphasizes the need for careful evaluation to distinguish difficult acne from similar conditions.
July 2025 in “Journal of Investigative Dermatology” Acne involves increased lipid production and inflammation, affecting skin cell behavior and treatment resistance.
research Acne
4 citations
,
January 2019 This analysis examines acne vulgaris using an integrative approach, highlighting its links with psychopathology, lifestyle, and diet, but reports no new results.
28 citations
,
January 1986 in “International Journal of Dermatology” This case study describes a pregnant woman who developed a pruritic rash with follicular lesions containing yeast-like organisms, resistant to conventional acne treatments.
1 citations
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March 2017 in “InTech eBooks” This article discusses systemic diseases and syndromes associated with acne and provides no research results; the authors highlight the need for increased recognition of these conditions.
9 citations
,
September 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Pseudofolliculitis cutis causes painful skin bumps and needs proper shaving and treatments to manage.
7 citations
,
February 2006 in “Clinical and Experimental Dermatology” This clinical report details the case of a 22-year-old man experiencing severe pustular eruptions on his chest and back, which improved after increasing minocycline to 100 mg twice daily.
83 citations
,
September 1993 in “Endocrinology and Metabolism Clinics of North America”
14 citations
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April 2014 in “International Journal of Cosmetic Science” This article discusses the multifactorial etiopathogenesis of acne vulgaris, highlighting the roles of sebum production, keratosis, bacterial development, and inflammatory mediators, but reports no new clinical results.
July 2011 in “Journal of Pediatric and Adolescent Gynecology” This report discusses a teenager with blistering of localized epidermolysis bullosa simplex—Weber Cockayne type, recommending referral to dermatology, and includes no new clinical trials or broader conclusions.
January 2026 in “Pharmaceutical journal/The pharmaceutical journal” This article discusses acne vulgaris as a prevalent skin disease affecting the pilosebaceous unit and provides no new clinical findings.
August 2016 in “Journal of evolution of medical and dental sciences” This study describes the clinical profile of acne vulgaris in patients from a tertiary care hospital, noting a male predominance and frequent occurrence of post acne hyperpigmentation.
research Acne
231 citations
,
April 2005 in “The New England Journal of Medicine” This article discusses the treatment considerations for a 17-year-old boy with a six-month history of acne but reports no new research findings.
1 citations
,
February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” This study elucidates a mechanism for acne-like skin toxicity caused by EGFR/MEK inhibitors, involving an interaction with skin bacteria to trigger inflammation, which supports existing antibiotic treatment practices.
2 citations
,
July 2008 in “Paediatrics & child health” This case report describes a 10-year-old girl with advanced puberty signs and resistant acne, highlighting potential early-onset puberty with associated growth patterns.
466 citations
,
June 2009 in “Experimental dermatology” This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.
68 citations
,
May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used single-cell transcriptomic analysis to identify a specific cell population in acne patients' non-lesional skin, providing evidence for the comedone switch hypothesis by suggesting a shift towards infundibular differentiation at the expense of sebaceous gland maintenance.
14 citations
,
January 2020 in “Dermatology Online Journal” This article reviews the link between certain dietary supplements, such as vitamins B6/B12, iodine, whey, and muscle-building products, and acne, emphasizing the need for dermatologists to discuss supplement use with patients; it reports no new results.
1 citations
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December 1997 in “Archives of dermatology” This report describes a case of trichostasis spinulosa, a condition with pruritic, black papules on the face caused by keratotic plugs with embedded vellus hairs.
January 2018 in “Springer eBooks” The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.
12 citations
,
September 2003 in “Current paediatrics” This review discusses topical and oral treatments for acne in children and provides guidance on tailoring these treatments according to acne severity, but it reports no new clinical results.
21 citations
,
April 2011 in “Clinical Cosmetic and Investigational Dermatology” This review discusses treatments for acne of varying severity and hormonal influences but reports no new clinical results; it suggests specific therapies for different acne types and highlights considerations for female patients.
June 2026 in “Indian Journal of Postgraduate Dermatology” In this reported case, a 50-year-old man developed an acneiform rash, a common skin side effect of EGFR inhibitor therapy, after starting lapatinib for breast cancer; treatment with doxycycline and hydrocortisone cream led to significant improvement within one week.
November 2010 in “International Journal of Dermatology and Venereology” This article discusses the clinical manifestations and management strategies of skin side effects from epidermal growth factor receptor inhibitors, but reports no new clinical findings.
19 citations
,
April 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.
47 citations
,
January 2015 in “Dermatology” This review revisits mechanisms underlying acne lesion formation and suggests that preventing comedone development requires controlling critical factors in the pilosebaceous follicle before acne involvement.
July 2025 in “International Journal of Pharmacognosy and Pharmaceutical Sciences” This review discusses acne's common triggers, challenges with conventional treatments, and the potential of alternative therapies to reduce side effects and enhance outcomes, highlighting an increasing interest in safer approaches due to the limitations of current topical options.
January 2016 in “Springer eBooks” Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.
This chapter discusses the mechanisms, presentation, course, differential diagnosis, and treatment of drug-induced skin reactions and reports no new clinical results.