Skin Reactions Caused by Epidermal Growth Factor Receptor Inhibitors and Their Management

November 2010 in “ International Journal of Dermatology and Venereology ”

Dandan Song, Ren-qi Lu

epidermal growth factor receptor inhibitors EGFRIs acneiform eruptions xerosis fissures telangiectasia hyperpigmentation hair changes paronychia

TLDR EGFR inhibitors can cause skin issues, and managing these is important for treatment success.

Epidermal growth factor receptor inhibitors were effective in clinical cancer treatment but often caused skin-related toxic reactions, including acneiform rash, skin dryness, fissures, telangiectasia, pigmentation, hair changes, and paronychia. Actively treating these rashes and selecting appropriate medications were crucial for patients to continue anti-cancer therapy. The document summarized the clinical manifestations and treatment status of skin toxic reactions caused by these inhibitors to explore new treatment strategies.

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