TLDR EGFR inhibitors can cause skin issues, and managing these is important for treatment success.
Epidermal growth factor receptor inhibitors (EGFRIs) were effective in treating tumors but often caused skin-related side effects, including acneiform eruptions, xerosis, fissures, telangiectasia, hyperpigmentation, hair changes, and paronychia. Addressing these adverse reactions was crucial for improving patient compliance with EGFRI treatment. The document detailed the clinical manifestations and management strategies for these cutaneous side effects, aiming to enhance the understanding and development of new management approaches.
179 citations
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October 2018 in “American Journal of Clinical Dermatology” Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
29 citations
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September 2017 in “Oncology and therapy” The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
15 citations
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February 2017 in “Nursing Clinics of North America” Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.
43 citations
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January 2014 in “Indian Journal of Dermatology” EGFR inhibitors can cause skin issues like acne and dryness, but these can be managed without stopping treatment.
29 citations
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January 2012 in “Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy” New cancer drugs often cause skin and nail problems.
33 citations
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June 2009 in “Journal of Cutaneous Pathology” Erlotinib can cause nonscarring hair loss and itchy skin.
